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| カタログ番号 | MY413014 | ||||||||
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| 説明 |
Anti-Mouse MPO Polyclonal Antibody (MY413014) is a rabbit polyclonal antibody detecting MPO. Suitable for Mouse.
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| 種反応性 | Mouse | ||||||||
| アプリケーション | ELISA, IHC, WB | ||||||||
| 宿主種 | Rabbit | ||||||||
| クローン性 | Polyclonal | ||||||||
| アイソタイプ | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Mouse MPO (Ser289-Thr718). | ||||||||
| ターゲット | EC:1.11.2.2, MPO, Mpo, Myeloperoxidase, Myeloperoxidase heavy chain, Myeloperoxidase light chain | ||||||||
| エンドトキシンレベル | Please contact with the lab for this information. | ||||||||
| 純度 | >95% as determined by SDS-PAGE. | ||||||||
| 精製 | Purified by antigen affinity column. | ||||||||
| アクセッション番号 | P11247 | ||||||||
| 形態 | Liquid | ||||||||
| 保存バッファー | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 背景 | Myeloperoxidase (MPO) is a ~81 kDa protein. Part of the host defense system of polymorphonuclear leukocytes. It is responsible for microbicidal activity against a wide range of organisms. In the stimulated PMN, MPO catalyzes the production of hypohalous acids, primarily hypochlorous acid in physiologic situations, and other toxic intermediates that greatly enhance PMN microbicidal activity. Mediates the proteolytic cleavage of alpha-1-microglobulin to form t-alpha-1-microglobulin, which potently inhibits oxidation of low density lipoprotein particles and limits vascular damage. 1. Gaut, JP. et al. (2001) Proceedings of the National Academy of Sciences of the United States of America 98, 11961-6. PMID: 11593004 | ||||||||
| 注意事項 | For research use only |
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