Anti-Mouse Notch-1 Recombinant Antibody (SAA0270), APC (MW570137)

Name: Anti-Mouse Notch-1 Recombinant Antibody (SAA0270), APC
Brand: abinScience
SKU: MW570137
Price: 290 USD
Availability: InStock

Fiche technique Partager le produit Copier les informations

Prix(USD) :

Spécification :

50T
100T

Nombre :

Contactez-nous

Aperçu
Images
Reférences
Fiche technique
SDS

Aperçu

Numéro de catalogue	MW570137
Reactivité des espèces	Human, Mouse
Applications	ELISA, FCM
Espèce hôte	Rat
Clonalité	Monoclonal
Isotype	IgG1, kappa
ID de clone	SAA0270
Conjugaison	APC
Cible	hN1, TAN1, NEXT, NICD, Notch 1, Neurogenic locus notch homolog protein 1, Translocation-associated notch protein TAN-1, NOTCH1
Niveau d'endotoxines	Please contact with the lab for this information.
Produits associés	Rat IgG1, kappa Recombinant Isotype Control Antibody (ES26-14D1.11), APC
Numéro d'accès	Q01705
Forme	Liquid
Tampon de stockage	0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.
Stabilité et stockage	Store at 4°C for 12 months. Protect from light. Do not freeze.
Contexte	Neurogenic locus notch homolog protein 1 (NOTCH1) is a ~270 kDa protein. Functions as a receptor for membrane-bound ligands Jagged-1 (JAG1), Jagged-2 (JAG2) and Delta-1 (DLL1) to regulate cell-fate determination. Upon ligand activation through the released notch intracellular domain (NICD) it forms a transcriptional activator complex with RBPJ/RBPSUH and activates genes of the enhancer of split locus. Affects the implementation of differentiation, proliferation and apoptotic programs. Involved in angiogenesis; negatively regulates endothelial cell proliferation and migration and angiogenic sprouting. Involved in the maturation of both CD4(+) and CD8(+) cells in the thymus.
Reférences	1. NOTCH1 notch receptor 1 [Homo sapiens (human)] Gene ID: 4851, updated on 28-Oct-2019. [MW570137] 2. toyanova T, et al. Activation of Notch1 synergizes with multiple pathways in promoting castration-resistant prostate cancer. Proc Natl Acad Sci U S A. 2016 Oct 18;113(42):E6457-E6466. [MW570137]
Note	For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only.

Images

Reférences

Fiche technique

Anti-Mouse Notch-1 Recombinant Antibody (SAA0270), APC.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Protéines Recombinantes

Anticorps

Kits d'Essai