Anti-Mouse NR1I2 Polyclonal Antibody (MF641014)

Name: Anti-Mouse NR1I2 Polyclonal Antibody
Brand: abinScience
SKU: MF641014
Price: 168 USD
Availability: InStock

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Prix(USD) : --

Spécification :

50ug
100ug

Nombre :

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Reférences
Fiche technique
SDS

Aperçu

Numéro de catalogue

MF641014

Description

Anti-Mouse NR1I2 Polyclonal Antibody (MF641014) is a rabbit polyclonal antibody detecting Nr1i2. Suitable for Mouse and Rat.

Highlights

●Multi-Species — Cross-reactive for translational research.

Reactivité des espèces

Mouse, Rat

Applications

ELISA, IHC, WB

Espèce hôte

Rabbit

Clonalité

Polyclonal

Isotype

IgG

Immunogène

E. coli - derived recombinant Mouse NR1I2 (Thr141-Gly431).

Cible

Nr1i2, Nuclear receptor subfamily 1 group I member 2, Orphan nuclear receptor PXR, Pregnane X receptor, Pxr

Niveau d'endotoxines

Please contact with the lab for this information.

Purification

Purified by antigen affinity column.

Numéro d'accès

O54915

Forme

Liquid

Tampon de stockage

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.

Informations d'utilisation du produit

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Contexte

Nuclear receptor subfamily 1 group I member 2 (NR1I2) is a ~49 kDa protein. Nuclear receptor that acts as a transcription factor regulating genes involved in the metabolism and excretion of xenobiotics, drugs, and endogenous compounds. Activated by a broad range of endogenous steroids (e.g. pregnenolone, progesterone) and xenobiotics, including the antibiotic rifampicin and certain plant-derived metabolites. Upon ligand binding, translocates to the nucleus, forms a heterodimer with the retinoid X receptor/RXR, and binds to response elements in target promoters, leading to transcriptional activation. Target genes include cytochrome P450 enzymes such as CYP3A4 and ATP-binding cassette transporters including ABCB1/MDR1.

Note

For research use only

Images

Reférences

Fiche technique

Anti-Mouse NR1I2 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Protéines Recombinantes

Anticorps

Kits d'Essai

Anti-Mouse NR1I2 Polyclonal Antibody (MF641014)

Aperçu

Images

Reférences

Fiche technique

SDS