

| Número de catálogo | MX222014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Descripción |
Anti-Mouse OAZ1 Polyclonal Antibody (MX222014) is a rabbit polyclonal antibody detecting OAZ1. Suitable for Rat and Mouse.
Highlights
|
||||||||
| Reactividad de especies | Mouse, Rat | ||||||||
| Aplicaciones | ELISA, IHC, WB | ||||||||
| Especie huésped | Rabbit | ||||||||
| Clonalidad | Polyclonal | ||||||||
| Isotipo | IgG | ||||||||
| Inmunógeno | E. coli - derived recombinant Mouse OAZ1 (Ser91-Asp227). | ||||||||
| Objetivo | AZ1, OAZ, OAZ1, ODC-Az, Ornithine decarboxylase antizyme 1 | ||||||||
| Nivel de endotoxinas | Please contact with the lab for this information. | ||||||||
| Purificación | Purified by antigen affinity column. | ||||||||
| Número de acceso | P54369 | ||||||||
| Forma | Liquid | ||||||||
| Buffer de almacenamiento | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote. |
||||||||
| Información de uso del producto |
| ||||||||
| Fondo | Ornithine decarboxylase antizyme 1 (OAZ1) is a ~25 kDa protein. Ornithine decarboxylase (ODC) antizyme protein that negatively regulates ODC activity and intracellular polyamine biosynthesis and uptake in response to increased intracellular polyamine levels. Binds to ODC monomers, inhibiting the assembly of the functional ODC homodimer, and targets the monomers for ubiquitin-independent proteolytic destruction by the 26S proteasome. Triggers ODC degradation by inducing the exposure of a cryptic proteasome-interacting surface of ODC. Stabilizes AZIN2 by interfering with its ubiquitination. Also inhibits cellular uptake of polyamines by inactivating the polyamine uptake transporter. 1. López-Contreras, AJ. et al. (2006) The Journal of biological chemistry 281, 30896-906. PMID: 16916800 2. López-Contreras, AJ. et al. (2008) The Journal of biological chemistry 283, 20761-9. PMID: 18508777 3. Snapir, Z. et al. (2008) The Biochemical journal 410, 613-9. PMID: 18062773 4. López-Contreras, AJ. et al. (2009) Journal of cellular biochemistry 107, 732-40. PMID: 19449338 | ||||||||
| Nota | For research use only |
Contáctenos para cotizaciones personalizadas, solicitudes en masa y cualquier otro problema.
Correo: [email protected]
Acceso rápido
Contáctenos
+86-027-65523339
Edificio C, No. 666, Calle Shendunsi, Wuhan, 430206, China
中文
English
한국어
日本語
Español
Français
Русский