

| Número de catálogo | MY360014 | ||||||||
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| Descripción |
Anti-Mouse Osteocalcin/BGLAP/OC Polyclonal Antibody (MY360014) is a rabbit polyclonal antibody detecting Osteocalcin in ELISA, IHC, WB. Suitable for Mouse.
Highlights
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| Reactividad de especies | Mouse | ||||||||
| Aplicaciones | ELISA, IHC, WB | ||||||||
| Especie huésped | Rabbit | ||||||||
| Clonalidad | Polyclonal | ||||||||
| Isotipo | IgG | ||||||||
| Inmunógeno | E. coli - derived recombinant Mouse Osteocalcin/BGLAP/OC (Lys24-Ile95). | ||||||||
| Objetivo | Osteocalcin, OG1, Bone Gla protein, BGP, Gamma-carboxyglutamic acid-containing protein, Bglap, Ocn | ||||||||
| Purificación | Purified by antigen affinity column. | ||||||||
| Número de acceso | P86546 | ||||||||
| Forma | Liquid | ||||||||
| Buffer de almacenamiento | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote. |
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| Información de uso del producto |
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| Estabilidad y almacenamiento | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Fondo | Osteocalcin (BGLAP) is a ~10 kDa protein. The carboxylated form is one of the main organic components of the bone matrix, which constitutes 1-2% of the total bone protein. Acts as a negative regulator of bone formation and is required to limit bone formation without impairing bone resorption or mineralization. Binds strongly to apatite and calcium upon gamma-carboxylation; this modification is essential for bone metabolism. 1. Ducy, P. et al. (1996) Nature 382, 448-52. PMID: 8684484 2. Lee, NK. et al. (2007) Cell 130, 456-69. PMID: 17693256 | ||||||||
| Nota | For research use only. |
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