

| Número de catálogo | MY504014 | ||||||||
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| Descripción |
Anti-Mouse PLA2G1B Polyclonal Antibody (MY504014) is a rabbit polyclonal antibody detecting PLA2G1B. Suitable for Mouse.
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| Reactividad de especies | Mouse | ||||||||
| Aplicaciones | ELISA, IHC, WB | ||||||||
| Especie huésped | Rabbit | ||||||||
| Clonalidad | Polyclonal | ||||||||
| Isotipo | IgG | ||||||||
| Inmunógeno | E. coli - derived recombinant Mouse PLA2G1B (Ser20-Cys146). | ||||||||
| Objetivo | EC:3.1.1.4, Group IB phospholipase A2, PLA2, PLA2A, PLA2G1B, PPLA2, Phosphatidylcholine 2-acylhydrolase 1B, Phospholipase A2 | ||||||||
| Nivel de endotoxinas | Please contact with the lab for this information. | ||||||||
| Purificación | Purified by antigen affinity column. | ||||||||
| Número de acceso | Q9Z0Y2 | ||||||||
| Forma | Liquid | ||||||||
| Buffer de almacenamiento | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote. |
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| Información de uso del producto |
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| Fondo | Phospholipase A2 (PLA2G1B) is a ~16 kDa protein. Secretory calcium-dependent phospholipase A2 that primarily targets dietary phospholipids in the intestinal tract. Hydrolyzes the ester bond of the fatty acyl group attached at sn-2 position of phospholipids (phospholipase A2 activity) with preference for phosphatidylethanolamines and phosphatidylglycerols over phosphatidylcholines. May play a role in the biosynthesis of N-acyl ethanolamines that regulate energy metabolism and inflammation in the intestinal tract. Hydrolyzes N-acyl phosphatidylethanolamines to N-acyl lysophosphatidylethanolamines, which are further cleaved by a lysophospholipase D to release N-acyl ethanolamines. May act in an autocrine and paracrine manner. 1. Cupillard, L. et al. (1999) The Journal of biological chemistry 274, 7043-51. PMID: 10066760 2. Entwistle, LJ. et al. (2017) Cell host & microbe 22, 484-493.e5. PMID: 29024642 | ||||||||
| Nota | For research use only. |



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