

| Número de catálogo | MA272014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Descripción |
Anti-Mouse PLXNB3 Polyclonal Antibody (MA272014) is a rabbit polyclonal antibody detecting PLXNB3 in ELISA, IHC, WB. Suitable for Mouse.
Highlights
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| Reactividad de especies | Mouse | ||||||||
| Aplicaciones | ELISA, IHC, WB | ||||||||
| Especie huésped | Rabbit | ||||||||
| Clonalidad | Polyclonal | ||||||||
| Isotipo | IgG | ||||||||
| Inmunógeno | E. coli - derived recombinant Mouse PLXNB3 (Cys464-Asp609). | ||||||||
| Objetivo | PLXNB3, Plexin-B3, PLXN6, KIAA1206 | ||||||||
| Purificación | Purified by antigen affinity column. | ||||||||
| Número de acceso | Q9QY40 | ||||||||
| Forma | Liquid | ||||||||
| Buffer de almacenamiento | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote. |
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| Información de uso del producto |
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| Estabilidad y almacenamiento | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Fondo | Plexin-B3 (PLXNB3) is a ~208 kDa protein. Receptor for SEMA5A that plays a role in axon guidance, invasive growth and cell migration. Stimulates neurite outgrowth and mediates Ca(2+)/Mg(2+)-dependent cell aggregation. In glioma cells, SEMA5A stimulation of PLXNB3 results in the disassembly of F-actin stress fibers, disruption of focal adhesions and cellular collapse as well as inhibition of cell migration and invasion through ARHGDIA-mediated inactivation of RAC1. Seem to be non-essential for normal development and function of the central nervous system. | ||||||||
| Nota | For research use only. |
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