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Anti-Mouse Polyclonal Antibody (MY077014)

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Aperçu
Numéro de catalogueMY077014
Description
Anti-Mouse Polyclonal Antibody (MY077014) is a rabbit polyclonal antibody detecting BMP1 in ELISA, IHC, WB. Suitable for Human, Mouse.
Highlights
  • ●Affinity Purified — Minimal background and high purity for reliable results.
  • ●Multi-Application — Validated across multiple applications.
  • ●Multi-Species — Cross-reactive for translational research.
Reactivité des espècesHuman, Mouse
ApplicationsELISA, IHC, WB
Espèce hôteRabbit
ClonalitéPolyclonal
IsotypeIgG
Immunogène E. coli - derived recombinant Mouse BMP1 (Glu615-Ser848).
Cible Bone morphogenetic protein 1, BMP-1, 3.4.24.19, Mammalian tolloid protein, mTld, Procollagen C-proteinase, PCP, Bmp1
Purification Purified by antigen affinity column.
Numéro d'accès P98063
Forme Liquid
Tampon de stockage 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.
Informations d'utilisation du produit
Application Dilution
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Stabilité et stockage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Contexte

Bone morphogenetic protein 1 (BMP1) is a ~111 kDa protein. Metalloprotease that plays key roles in regulating the formation of the extracellular matrix (ECM) via processing of various precursor proteins into mature functional enzymes or structural proteins. Thereby participates in several developmental and physiological processes such as cartilage and bone formation, muscle growth and homeostasis, wound healing and tissue repair. Roles in ECM formation include cleavage of the C-terminal propeptides from procollagens such as procollagen I, II and III or the proteolytic activation of the enzyme lysyl oxidase LOX, necessary to formation of covalent cross-links in collagen and elastic fibers. Additional substrates include matricellular thrombospondin-1/THBS1 whose cleavage leads to cell adhesion disruption and TGF-beta activation.

1. Muir, AM. et al. (2014) Human molecular genetics 23, 3085-101. PMID: 24419319
2. Wang, J. et al. (2017) Journal of dental research 96, 578-585. PMID: 28068493
3. Suzuki, N. et al. (1996) Development (Cambridge, England) 122, 3587-95. PMID: 8951074
4. Maruhashi, T. et al. (2010) The Journal of biological chemistry 285, 13294-303. PMID: 20181949
Note For research use only.
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Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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Anti-Mouse Polyclonal Antibody

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