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Anti-Mouse ROR1 Recombinant Antibody (R11) (MX065107)

Anti-Mouse ROR1 Recombinant Antibody (R11)
Anti-Mouse ROR1 Recombinant Antibody (R11)
Anti-Mouse ROR1 Recombinant Antibody (R11)
Anti-Mouse ROR1 Recombinant Antibody (R11)
Precio(USD):
Especificación:
  • 50ug
  • 100ug
Número:
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Vista general
Número de catálogoMX065107
Reactividad de especiesHuman, Mouse
AplicacionesELISA, FCM
Especie huéspedMouse
ClonalidadMonoclonal
IsotipoIgG2a, kappa
ID de clonR11
Aplicaciones probadas FCM
Objetivo Neurotrophic tyrosine kinase, receptor-related 1, Inactive tyrosine-protein kinase transmembrane receptor ROR1, NTRKR1, ROR1
Nivel de endotoxinas Please contact with the lab for this information.
Pureza >95% as determined by SDS-PAGE.
Purificación Protein A/G purified from cell culture supernatant.
Número de acceso Q9Z139
Forma Liquid
Buffer de almacenamiento 0.01M PBS pH 7.4

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.

Estabilidad y almacenamiento Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Fondo

Inactive tyrosine-protein kinase transmembrane receptor ROR1 (NTRKR1) is a ~104 kDa protein. Has very low kinase activity in vitro and is unlikely to function as a tyrosine kinase in vivo. Receptor for ligand WNT5A which activate downstream NFkB signaling pathway and may result in the inhibition of WNT3A-mediated signaling. In inner ear, crucial for spiral ganglion neurons to innervate auditory hair cells. Via IGFBP5 ligand, forms a complex with ERBB2 to enhance CREB oncogenic signaling.

1. Diaz-Horta, O. et al. (2016) Proceedings of the National Academy of Sciences of the United States of America 113, 5993-8. PMID: 27162350
Nota For research use only.
Imágenes
  • Anti-Mouse ROR1 Recombinant Antibody (R11)

    Bioactivity

    Detects ROR1 in indirect ELISAs.

  • Anti-Mouse ROR1 Recombinant Antibody (R11)

    Flow Cytometry

    Flow cytometry analysis with Anti-Mouse ROR1 mAb (R11) 5 μg/ml (MX065107) on XtenCHO cells transfected with Mouse ROR1 (green histogram) or the isotype control (FMB96750) (blue histogram).

Referencias
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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