



| Número de catálogo | MX065107 |
|---|---|
| Reactividad de especies | Human, Mouse |
| Aplicaciones | ELISA, FCM |
| Especie huésped | Mouse |
| Clonalidad | Monoclonal |
| Isotipo | IgG2a, kappa |
| ID de clon | R11 |
| Aplicaciones probadas | FCM |
| Objetivo | Neurotrophic tyrosine kinase, receptor-related 1, Inactive tyrosine-protein kinase transmembrane receptor ROR1, NTRKR1, ROR1 |
| Nivel de endotoxinas | Please contact with the lab for this information. |
| Pureza | >95% as determined by SDS-PAGE. |
| Purificación | Protein A/G purified from cell culture supernatant. |
| Número de acceso | Q9Z139 |
| Forma | Liquid |
| Buffer de almacenamiento | 0.01M PBS pH 7.4 Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote. |
| Estabilidad y almacenamiento | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. |
| Fondo | Inactive tyrosine-protein kinase transmembrane receptor ROR1 (NTRKR1) is a ~104 kDa protein. Has very low kinase activity in vitro and is unlikely to function as a tyrosine kinase in vivo. Receptor for ligand WNT5A which activate downstream NFkB signaling pathway and may result in the inhibition of WNT3A-mediated signaling. In inner ear, crucial for spiral ganglion neurons to innervate auditory hair cells. Via IGFBP5 ligand, forms a complex with ERBB2 to enhance CREB oncogenic signaling. 1. Diaz-Horta, O. et al. (2016) Proceedings of the National Academy of Sciences of the United States of America 113, 5993-8. PMID: 27162350 |
| Nota | For research use only. |

Detects ROR1 in indirect ELISAs.

Flow cytometry analysis with Anti-Mouse ROR1 mAb (R11) 5 μg/ml (MX065107) on XtenCHO cells transfected with Mouse ROR1 (green histogram) or the isotype control (FMB96750) (blue histogram).




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