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| カタログ番号 | MY242014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 種反応性 | Mouse | ||||||||
| アプリケーション | ELISA, IHC, WB | ||||||||
| 宿主種 | Rabbit | ||||||||
| クローン性 | Polyclonal | ||||||||
| アイソタイプ | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Mouse S100A8 (Pro2-Glu89). | ||||||||
| ターゲット | S100 calcium-binding protein A8, Urinary stone protein band A, MRP8, Cystic fibrosis antigen, Calprotectin L1L subunit, MRP-8, p8, Calgranulin-A, Migration inhibitory factor-related protein 8, Leukocyte L1 complex light chain, S100A8, Protein S100-A8, CAGA, CFAG | ||||||||
| 精製 | Purified by antigen affinity column. | ||||||||
| アクセッション番号 | P27005 | ||||||||
| 形態 | Liquid | ||||||||
| 保存バッファー | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Protein S100-A8 (S100A8) is a ~10 kDa protein. S100A8 is a calcium- and zinc-binding protein which plays a prominent role in the regulation of inflammatory processes and immune response. It can induce neutrophil chemotaxis and adhesion. Predominantly found as calprotectin (S100A8/A9) which has a wide plethora of intra- and extracellular functions. The intracellular functions include: facilitating leukocyte arachidonic acid trafficking and metabolism, modulation of the tubulin-dependent cytoskeleton during migration of phagocytes and activation of the neutrophilic NADPH-oxidase. Also participates in regulatory T-cell differentiation together with CD69. | ||||||||
| 注意事項 | For research use only. |
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