Anti-Mouse S100A9 Polyclonal Antibody (MY562014)

Name: Anti-Mouse S100A9 Polyclonal Antibody
Brand: abinScience
SKU: MY562014
Price: 96 USD
Availability: InStock

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Reférences
Fiche technique
SDS

Aperçu

Numéro de catalogue

MY562014

Description

Anti-Mouse S100A9 Polyclonal Antibody (MY562014) is a rabbit polyclonal antibody detecting S100a9 in ELISA, IHC, WB. Suitable for Mouse.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

Reactivité des espèces

Mouse

Applications

ELISA, IHC, WB

Espèce hôte

Rabbit

Clonalité

Polyclonal

Isotype

IgG

Immunogène

E. coli - derived recombinant Mouse S100A9 (Ala2-Lys113).

Cible

Protein S100-A9, Calgranulin-B, Leukocyte L1 complex heavy chain, Migration inhibitory factor-related protein 14, MRP-14, p14, S100 calcium-binding protein A9, S100a9, Cagb, Mrp14

Purification

Purified by antigen affinity column.

Numéro d'accès

P31725

Forme

Liquid

Tampon de stockage

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.

Informations d'utilisation du produit

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stabilité et stockage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Contexte

Protein S100-A9 (S100A9) is a ~13 kDa protein. S100A9 is a calcium- and zinc-binding protein which plays a prominent role in the regulation of inflammatory processes and immune response. It can induce neutrophil chemotaxis, adhesion, can increase the bactericidal activity of neutrophils by promoting phagocytosis via activation of SYK, PI3K/AKT, and ERK1/2 and can induce degranulation of neutrophils by a MAPK-dependent mechanism. Predominantly found as calprotectin (S100A8/A9) which has a wide plethora of intra- and extracellular functions. The intracellular functions include: facilitating leukocyte arachidonic acid trafficking and metabolism, modulation of the tubulin-dependent cytoskeleton during migration of phagocytes and activation of the neutrophilic NADPH-oxidase. Also participates in regulatory T-cell differentiation together with CD69.

1. Vogl, T. et al. (2004) Blood 104, 4260-8. PMID: 15331440

2. Vogl, T. et al. (2007) Nature medicine 13, 1042-9. PMID: 17767165

3. Boyd, JH. et al. (2008) Circulation research 102, 1239-46. PMID: 18403730

4. Björk, P. et al. (2009) PLoS biology 7, e97. PMID: 19402754

5. Riva, M. et al. (2012) Immunology 137, 172-82. PMID: 22804476

6. Daitoku, H. et al. (2021) The Journal of biological chemistry 297, 101230. PMID: 34562450

7. Averill, MM. et al. (2011) Circulation 123, 1216-26. PMID: 21382888

Note

For research use only.

Images

Western blot

Western blot analysis was performed using anti-S100A9 polyclonal antibody at 1ug/mL on various samples.
Lane 1: Mouse spleen lysate
Lane 2: Rat spleen lysate

Reférences

Fiche technique

Anti-Mouse S100A9 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

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