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Anti-Mouse Serpinb1a Polyclonal Antibody (MD634014)

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Vista general
Número de catálogoMD634014
Descripción
Anti-Mouse Serpinb1a Polyclonal Antibody (MD634014) is a rabbit polyclonal antibody detecting Serpinb1a. Suitable for Rat and Mouse.
Highlights
  • ●Multi-Species — Cross-reactive for translational research.
Reactividad de especiesMouse, Rat
AplicacionesELISA, IHC, WB
Especie huéspedRabbit
ClonalidadPolyclonal
IsotipoIgG
Inmunógeno E. coli - derived recombinant Mouse Serpinb1a (Met1-Pro379).
Objetivo Leukocyte elastase inhibitor A, Serine protease inhibitor EIA, Serpin B1a, Serpinb1, Serpinb1a
Nivel de endotoxinas Please contact with the lab for this information.
Purificación Purified by antigen affinity column.
Número de acceso Q9D154
Forma Liquid
Buffer de almacenamiento 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.
Información de uso del producto
Aplicación Dilución
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Fondo

Leukocyte elastase inhibitor A (Serpinb1a) is a ~42 kDa protein. Neutrophil serine protease inhibitor that plays an essential role in the regulation of the innate immune response, inflammation and cellular homeostasis. Acts primarily to protect the cell from proteases released in the cytoplasm during stress or infection. These proteases are important in killing microbes but when released from granules, these potent enzymes also destroy host proteins and contribute to mortality. Regulates the activity of the neutrophil proteases elastase, cathepsin G, proteinase-3, chymase, chymotrypsin, and kallikrein-3. Also acts as a potent intracellular inhibitor of granzyme H.

1. Benarafa, C. et al. (2007) The Journal of experimental medicine 204, 1901-9. PMID: 17664292
2. Benarafa, C. et al. (2011) Journal of leukocyte biology 90, 21-9. PMID: 21248149
3. Benarafa, C. (2011) Methods in enzymology 499, 135-48. PMID: 21683252
4. Choi, YJ. et al. (2019) Nature immunology 20, 276-287. PMID: 30692621
5. Benarafa, C. et al. (2002) The Journal of biological chemistry 277, 42028-33. PMID: 12189154
6. El Ouaamari, A. et al. (2016) Cell metabolism 23, 194-205. PMID: 26701651
Nota For research use only
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Datasheet
Download SDS PDF
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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