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Anti-Mouse Serpinb1a Polyclonal Antibody (MD634014)

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Aperçu
Numéro de catalogueMD634014
Description
Anti-Mouse Serpinb1a Polyclonal Antibody (MD634014) is a rabbit polyclonal antibody detecting Serpinb1a. Suitable for Rat and Mouse.
Highlights
  • ●Multi-Species — Cross-reactive for translational research.
Reactivité des espècesMouse, Rat
ApplicationsELISA, IHC, WB
Espèce hôteRabbit
ClonalitéPolyclonal
IsotypeIgG
Immunogène E. coli - derived recombinant Mouse Serpinb1a (Met1-Pro379).
Cible Leukocyte elastase inhibitor A, Serine protease inhibitor EIA, Serpin B1a, Serpinb1, Serpinb1a
Niveau d'endotoxines Please contact with the lab for this information.
Purification Purified by antigen affinity column.
Numéro d'accès Q9D154
Forme Liquid
Tampon de stockage 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.
Informations d'utilisation du produit
Application Dilution
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Contexte

Leukocyte elastase inhibitor A (Serpinb1a) is a ~42 kDa protein. Neutrophil serine protease inhibitor that plays an essential role in the regulation of the innate immune response, inflammation and cellular homeostasis. Acts primarily to protect the cell from proteases released in the cytoplasm during stress or infection. These proteases are important in killing microbes but when released from granules, these potent enzymes also destroy host proteins and contribute to mortality. Regulates the activity of the neutrophil proteases elastase, cathepsin G, proteinase-3, chymase, chymotrypsin, and kallikrein-3. Also acts as a potent intracellular inhibitor of granzyme H.

1. Benarafa, C. et al. (2007) The Journal of experimental medicine 204, 1901-9. PMID: 17664292
2. Benarafa, C. et al. (2011) Journal of leukocyte biology 90, 21-9. PMID: 21248149
3. Benarafa, C. (2011) Methods in enzymology 499, 135-48. PMID: 21683252
4. Choi, YJ. et al. (2019) Nature immunology 20, 276-287. PMID: 30692621
5. Benarafa, C. et al. (2002) The Journal of biological chemistry 277, 42028-33. PMID: 12189154
6. El Ouaamari, A. et al. (2016) Cell metabolism 23, 194-205. PMID: 26701651
Note For research use only
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Fiche technique
Download SDS PDF
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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Anti-Mouse Serpinb1a Polyclonal Antibody

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