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| カタログ番号 | MD634014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 説明 |
Anti-Mouse Serpinb1a Polyclonal Antibody (MD634014) is a rabbit polyclonal antibody detecting Serpinb1a. Suitable for Rat and Mouse.
Highlights
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| 種反応性 | Mouse, Rat | ||||||||
| アプリケーション | ELISA, IHC, WB | ||||||||
| 宿主種 | Rabbit | ||||||||
| クローン性 | Polyclonal | ||||||||
| アイソタイプ | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Mouse Serpinb1a (Met1-Pro379). | ||||||||
| ターゲット | Leukocyte elastase inhibitor A, Serine protease inhibitor EIA, Serpin B1a, Serpinb1, Serpinb1a | ||||||||
| エンドトキシンレベル | Please contact with the lab for this information. | ||||||||
| 精製 | Purified by antigen affinity column. | ||||||||
| アクセッション番号 | Q9D154 | ||||||||
| 形態 | Liquid | ||||||||
| 保存バッファー | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 背景 | Leukocyte elastase inhibitor A (Serpinb1a) is a ~42 kDa protein. Neutrophil serine protease inhibitor that plays an essential role in the regulation of the innate immune response, inflammation and cellular homeostasis. Acts primarily to protect the cell from proteases released in the cytoplasm during stress or infection. These proteases are important in killing microbes but when released from granules, these potent enzymes also destroy host proteins and contribute to mortality. Regulates the activity of the neutrophil proteases elastase, cathepsin G, proteinase-3, chymase, chymotrypsin, and kallikrein-3. Also acts as a potent intracellular inhibitor of granzyme H. 1. Benarafa, C. et al. (2007) The Journal of experimental medicine 204, 1901-9. PMID: 17664292 2. Benarafa, C. et al. (2011) Journal of leukocyte biology 90, 21-9. PMID: 21248149 3. Benarafa, C. (2011) Methods in enzymology 499, 135-48. PMID: 21683252 4. Choi, YJ. et al. (2019) Nature immunology 20, 276-287. PMID: 30692621 5. Benarafa, C. et al. (2002) The Journal of biological chemistry 277, 42028-33. PMID: 12189154 6. El Ouaamari, A. et al. (2016) Cell metabolism 23, 194-205. PMID: 26701651 | ||||||||
| 注意事項 | For research use only |
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