Anti-Mouse Sonic Hedgehog/SHH Recombinant Antibody (6D7) (MS826107)

Name: Anti-Mouse Sonic Hedgehog/SHH Recombinant Antibody (6D7)
Brand: abinScience
SKU: MS826107
Price: 191 USD
Availability: InStock

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Aperçu

Numéro de catalogue	MS826107
Reactivité des espèces	Human, Mouse
Applications	ELISA, FCM
Espèce hôte	Rat
Clonalité	Monoclonal
Isotype	IgG1, kappa
ID de clone	6D7
Cible	ShhNC, Sonic hedgehog protein, Shh N-terminal processed signaling domains, SHH, Shh unprocessed N-terminal signaling and C-terminal autoprocessing domains, ShhN, ShhNp, HHG-1
Niveau d'endotoxines	< 10 EU/mg
Pureté	>95% as determined by SDS-PAGE.
Purification	Protein A/G purified from cell culture supernatant.
Numéro d'accès	Q62226
Forme	Liquid
Tampon de stockage	0.01M PBS pH 7.4. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.
Stabilité et stockage	Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Contexte	Sonic hedgehog protein (SHH) is a ~47 kDa protein. The C-terminal part of the sonic hedgehog protein precursor displays an autoproteolysis and a cholesterol transferase activity. Both activities result in the cleavage of the full-length protein into two parts (ShhN and ShhC) followed by the covalent attachment of a cholesterol moiety to the C-terminal of the newly generated ShhN. Both activities occur in the reticulum endoplasmic. Once cleaved, ShhC is degraded in the endoplasmic reticulum. 1. Roelink, H. et al. (1995) Cell 81, 445-55. PMID: 7736596 2. Bumcrot, DA. et al. (1995) Molecular and cellular biology 15, 2294-303. PMID: 7891723 3. Porter, JA. et al. (1996) Science (New York, N.Y.) 274, 255-9. PMID: 8824192 4. Chen, X. et al. (2011) The Journal of cell biology 192, 825-38. PMID: 21357747
Note	For research use only.

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SDS-PAGE

SDS-PAGE for Anti-Mouse SHH Antibody (6D7)

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Anti-Mouse Sonic Hedgehog/SHH Recombinant Antibody (6D7).pdf

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