

| Numéro de catalogue | MX937014 | ||||||||
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| Description |
Anti-Mouse SLURP1 Polyclonal Antibody (MX937014) is a rabbit polyclonal antibody detecting Secreted Ly-6/uPAR-related protein 1; SLURP-1; ARS component B; Slurp1; Ars in ELISA, IHC, WB. Suitable for Mouse.
Highlights
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| Reactivité des espèces | Mouse | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Espèce hôte | Rabbit | ||||||||
| Clonalité | Polyclonal | ||||||||
| Isotype | IgG | ||||||||
| Immunogène | E. coli - derived recombinant mouse SLURP1 (Phe23-Leu110). | ||||||||
| Cible | Secreted Ly-6/uPAR-related protein 1; SLURP-1; ARS component B; Slurp1; Ars | ||||||||
| Niveau d'endotoxines | Please contact with the lab for this information. | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Numéro d'accès | Q9Z0K7 | ||||||||
| Forme | Liquid | ||||||||
| Tampon de stockage | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot. |
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| Informations d'utilisation du produit |
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| Stabilité et stockage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Contexte | Secreted Ly-6/uPAR-related protein 1 (SLURP1) is a ~12 kDa protein. Has an antitumor activity. Was found to be a marker of late differentiation of the skin. Implicated in maintaining the physiological and structural integrity of the keratinocyte layers of the skin. In vitro down-regulates keratinocyte proliferation; the function may involve the proposed role as modulator of nicotinic acetylcholine receptors (nAChRs) activity. In vitro inhibits alpha-7-dependent nAChR currents in an allosteric manner. 1. Moriwaki, Y. et al. (2007) Life sciences 80, 2365-8. PMID: 17286989 2. Swamynathan, S. et al. (2012) Investigative ophthalmology & visual science 53, 8433-46. PMID: 23139280 3. Swamynathan, S. et al. (2014) Investigative ophthalmology & visual science 55, 6251-61. PMID: 25168896 | ||||||||
| Note | For research use only |
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