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| カタログ番号 | MY108014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 説明 |
Anti-Mouse TH Polyclonal Antibody (MY108014) is a rabbit polyclonal antibody detecting Mouse TH in ELISA, IHC, WB. Suitable for Mouse.
Highlights
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| 種反応性 | Human, Mouse, Rat | ||||||||
| アプリケーション | ELISA, IHC, WB | ||||||||
| 宿主種 | Rabbit | ||||||||
| クローン性 | Polyclonal | ||||||||
| アイソタイプ | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Mouse TH (Lys170-Arg454). | ||||||||
| ターゲット | Tyrosine 3-monooxygenase, 1.14.16.2, Tyrosine 3-hydroxylase, TH, Th | ||||||||
| 精製 | Purified by antigen affinity column. | ||||||||
| アクセッション番号 | P24529 | ||||||||
| 形態 | Liquid | ||||||||
| 保存バッファー | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Tyrosine 3-monooxygenase (TH) is a ~55 kDa protein. Catalyzes the conversion of L-tyrosine to L-dihydroxyphenylalanine (L-Dopa), the rate-limiting step in the biosynthesis of catecholamines, dopamine, noradrenaline, and adrenaline. Uses tetrahydrobiopterin and molecular oxygen to convert tyrosine to L-Dopa. In addition to tyrosine, is able to catalyze the hydroxylation of phenylalanine and tryptophan with lower specificity. Positively regulates the regression of retinal hyaloid vessels during postnatal development. 1. Nguyen, MT. et al. (2019) Nature cell biology 21, 420-429. PMID: 30936473 | ||||||||
| 注意事項 | For research use only. |
Western blot analysis was performed using anti-TH polyclonal antibody at 1ug/mL on various samples.
Lane 1: PC-12 cell lysate
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