

| Número de catálogo | MA149014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Descripción |
Anti-Mouse Timd2/G9D3 protein Polyclonal Antibody (MA149014) is a rabbit polyclonal antibody detecting Timd2/G9D3 protein in ELISA, IHC, WB. Suitable for Mouse.
Highlights
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| Reactividad de especies | Mouse | ||||||||
| Aplicaciones | ELISA, IHC, WB | ||||||||
| Especie huésped | Rabbit | ||||||||
| Clonalidad | Polyclonal | ||||||||
| Isotipo | IgG | ||||||||
| Inmunógeno | E. coli - derived recombinant Mouse Timd2/G9D3 protein (Ser21-Glu129). | ||||||||
| Objetivo | T cell immunoglobulin and mucin domain containing 2, Timd2, G9D3 protein | ||||||||
| Purificación | Purified by antigen affinity column. | ||||||||
| Número de acceso | Q8R183 | ||||||||
| Forma | Liquid | ||||||||
| Buffer de almacenamiento | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote. |
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| Información de uso del producto |
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| Estabilidad y almacenamiento | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Fondo | T-cell immunoglobulin and mucin domain-containing protein 2 (Timd2/G9D3 protein) is a ~33 kDa protein. Cell surface glycoprotein that participates in iron homeostasis in the liver, the kidney, the retina and oligodendrocytes by acting as a receptor of H-ferritin. Mechanistically, mediates iron-containing ferritin uptake via an endocytic pathway, trafficking to endosomes and subsequently to lysosomes. Plays also an important role in the regulation of Th2 immunity. Receptor for SEMA4A involved in the regulation of T-cell function, enhancing T-cell activation. 1. Chen, TT. et al. (2005) The Journal of experimental medicine 202, 955-65. PMID: 16203866 2. Valença, A. et al. (2021) Experimental eye research 202, 108292. PMID: 33065090 3. Chakravarti, S. et al. (2005) The Journal of experimental medicine 202, 437-44. PMID: 16043519 4. Han, J. et al. (2011) PloS one 6, e23800. PMID: 21886823 5. Kumanogoh, A. et al. (2002) Nature 419, 629-33. PMID: 12374982 | ||||||||
| Nota | For research use only. |
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