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| カタログ番号 | MA149014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 説明 |
Anti-Mouse Timd2/G9D3 protein Polyclonal Antibody (MA149014) is a rabbit polyclonal antibody detecting Timd2/G9D3 protein in ELISA, IHC, WB. Suitable for Mouse.
Highlights
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| 種反応性 | Mouse | ||||||||
| アプリケーション | ELISA, IHC, WB | ||||||||
| 宿主種 | Rabbit | ||||||||
| クローン性 | Polyclonal | ||||||||
| アイソタイプ | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Mouse Timd2/G9D3 protein (Ser21-Glu129). | ||||||||
| ターゲット | T cell immunoglobulin and mucin domain containing 2, Timd2, G9D3 protein | ||||||||
| 精製 | Purified by antigen affinity column. | ||||||||
| アクセッション番号 | Q8R183 | ||||||||
| 形態 | Liquid | ||||||||
| 保存バッファー | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | T-cell immunoglobulin and mucin domain-containing protein 2 (Timd2/G9D3 protein) is a ~33 kDa protein. Cell surface glycoprotein that participates in iron homeostasis in the liver, the kidney, the retina and oligodendrocytes by acting as a receptor of H-ferritin. Mechanistically, mediates iron-containing ferritin uptake via an endocytic pathway, trafficking to endosomes and subsequently to lysosomes. Plays also an important role in the regulation of Th2 immunity. Receptor for SEMA4A involved in the regulation of T-cell function, enhancing T-cell activation. 1. Chen, TT. et al. (2005) The Journal of experimental medicine 202, 955-65. PMID: 16203866 2. Valença, A. et al. (2021) Experimental eye research 202, 108292. PMID: 33065090 3. Chakravarti, S. et al. (2005) The Journal of experimental medicine 202, 437-44. PMID: 16043519 4. Han, J. et al. (2011) PloS one 6, e23800. PMID: 21886823 5. Kumanogoh, A. et al. (2002) Nature 419, 629-33. PMID: 12374982 | ||||||||
| 注意事項 | For research use only. |
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