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Anti-Mouse GITR/TNFRSF18 Polyclonal Antibody (MP087014)

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Aperçu
Numéro de catalogueMP087014
Description
Anti-Mouse GITR/TNFRSF18 Polyclonal Antibody (MP087014) is a rabbit polyclonal antibody detecting GITR/TNFRSF18 in ELISA, IHC, WB. Suitable for Mouse.
Highlights
  • ●Affinity Purified — Minimal background and high purity for reliable results.
  • ●Multi-Application — Validated across multiple applications.
Reactivité des espècesMouse
ApplicationsELISA, IHC, WB
Espèce hôteRabbit
ClonalitéPolyclonal
IsotypeIgG
Immunogène E. coli - derived recombinant Mouse TNFSF18 (Glu50-Ser173).
Cible Tumor necrosis factor ligand superfamily member 18 (GITR ligand) (GITRL) (Glucocorticoid-induced TNF-related ligand)
Niveau d'endotoxines Please contact with the lab for this information.
Pureté >95% as determined by SDS-PAGE.
Purification Purified by antigen affinity column.
Numéro d'accès Q7TS55
Forme Liquid
Tampon de stockage 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.
Informations d'utilisation du produit
Application Dilution
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Stabilité et stockage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Contexte

Tumor necrosis factor ligand superfamily member 18 (TNFSF18/GITRL) is a ~19 kDa protein. Cytokine that binds to TNFRSF18/AITR/GITR. Regulates T-cell responses. Can function as costimulator and lower the threshold for T-cell activation and T-cell proliferation. Important for interactions between activated T-lymphocytes and endothelial cells. Mediates activation of NF-kappa-B.

1. Yu, KY. et al. (2003) Biochemical and biophysical research communications 310, 433-8. PMID: 14521928
2. Kim, JD. et al. (2003) Genes and immunity 4, 564-9. PMID: 14647196
3. Tone, M. et al. (2003) Proceedings of the National Academy of Sciences of the United States of America 100, 15059-64. PMID: 14608036
4. Ji, HB. et al. (2004) Journal of immunology (Baltimore, Md. : 1950) 172, 5823-7. PMID: 15128759
5. Zhou, Z. et al. (2008) Proceedings of the National Academy of Sciences of the United States of America 105, 641-5. PMID: 18178614
6. Lacal, PM. et al. (2013) The Journal of pharmacology and experimental therapeutics 347, 164-72. PMID: 23892569
7. Liao, G. et al. (2014) FASEB journal : official publication of the Federation of American Societies for Experimental Biology 28, 474-84. PMID: 24107315
Note For research use only.
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Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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Anti-Mouse GITR/TNFRSF18 Polyclonal Antibody

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