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| カタログ番号 | MP087014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 説明 |
Anti-Mouse GITR/TNFRSF18 Polyclonal Antibody (MP087014) is a rabbit polyclonal antibody detecting GITR/TNFRSF18 in ELISA, IHC, WB. Suitable for Mouse.
Highlights
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| 種反応性 | Mouse | ||||||||
| アプリケーション | ELISA, IHC, WB | ||||||||
| 宿主種 | Rabbit | ||||||||
| クローン性 | Polyclonal | ||||||||
| アイソタイプ | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Mouse TNFSF18 (Glu50-Ser173). | ||||||||
| ターゲット | Tumor necrosis factor ligand superfamily member 18 (GITR ligand) (GITRL) (Glucocorticoid-induced TNF-related ligand) | ||||||||
| エンドトキシンレベル | Please contact with the lab for this information. | ||||||||
| 純度 | >95% as determined by SDS-PAGE. | ||||||||
| 精製 | Purified by antigen affinity column. | ||||||||
| アクセッション番号 | Q7TS55 | ||||||||
| 形態 | Liquid | ||||||||
| 保存バッファー | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Tumor necrosis factor ligand superfamily member 18 (TNFSF18/GITRL) is a ~19 kDa protein. Cytokine that binds to TNFRSF18/AITR/GITR. Regulates T-cell responses. Can function as costimulator and lower the threshold for T-cell activation and T-cell proliferation. Important for interactions between activated T-lymphocytes and endothelial cells. Mediates activation of NF-kappa-B. 1. Yu, KY. et al. (2003) Biochemical and biophysical research communications 310, 433-8. PMID: 14521928 2. Kim, JD. et al. (2003) Genes and immunity 4, 564-9. PMID: 14647196 3. Tone, M. et al. (2003) Proceedings of the National Academy of Sciences of the United States of America 100, 15059-64. PMID: 14608036 4. Ji, HB. et al. (2004) Journal of immunology (Baltimore, Md. : 1950) 172, 5823-7. PMID: 15128759 5. Zhou, Z. et al. (2008) Proceedings of the National Academy of Sciences of the United States of America 105, 641-5. PMID: 18178614 6. Lacal, PM. et al. (2013) The Journal of pharmacology and experimental therapeutics 347, 164-72. PMID: 23892569 7. Liao, G. et al. (2014) FASEB journal : official publication of the Federation of American Societies for Experimental Biology 28, 474-84. PMID: 24107315 | ||||||||
| 注意事項 | For research use only. |
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