Anti-Mouse WDR45 Monoclonal Antibody (1A446) (MP297025)

Name: Anti-Mouse WDR45 Monoclonal Antibody (1A446)
Brand: abinScience
SKU: MP297025
Price: 194 USD
Availability: InStock

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Каталожный номер	MP297025
Описание	Anti-Mouse WDR45 Monoclonal Antibody (1A446) [1A446] (MP297025) is a mouse monoclonal antibody detecting Wdr45 in ELISA, WB. Suitable for Mouse. Highlights ●Recombinant — Superior batch-to-batch reproducibility with defined sequences.
Реактивность видов	Mouse
Применения	ELISA, WB
Хозяинский вид	Mouse
Клоональность	Monoclonal
Изотип	IgG2b
ID клона	1A446
Иммуноген	Recombinant Mouse WDR45 protein.
Цель	WD repeat domain phosphoinositide-interacting protein 4, WIPI-4, WD repeat domain X-linked 1, WD repeat-containing protein 45, Wdr45, DXImx38e, Wdrx1, Wipi4
Уровень эндотоксинов	Please contact with the lab for this information.
Чистота	>95% as determined by SDS-PAGE.
Очистка	Protein A/G purified from cell culture supernatant.
Номер доступа	Q91VM3
Форма	Liquid
Буфер хранения	0.01M PBS pH 7.4. Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии.
Устойчивость и хранение	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Фон	WD repeat domain phosphoinositide-interacting protein 4 (WDR45) is a ~39 kDa protein. Component of the autophagy machinery that controls the major intracellular degradation process by which cytoplasmic materials are packaged into autophagosomes and delivered to lysosomes for degradation. Binds phosphatidylinositol 3-phosphate (PtdIns3P). Activated by the STK11/AMPK signaling pathway upon starvation, WDR45 is involved in autophagosome assembly downstream of WIPI2, regulating the size of forming autophagosomes. Together with WIPI1, promotes ATG2 (ATG2A or ATG2B)-mediated lipid transfer by enhancing ATG2-association with phosphatidylinositol 3-monophosphate (PI3P)-containing membranes. Probably recruited to membranes through its PtdIns3P activity. 1. Saitsu, H. et al. (2013) Nature genetics 45, 445-9, 449e1. PMID: 23435086 2. Bakula, D. et al. (2017) Nature communications 8, 15637. PMID: 28561066 3. Maeda, S. et al. (2019) eLife 8. PMID: 31271352
Примечание	For research use only.

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SDS-PAGE for Anti-Mouse WDR45 Monoclonal Antibody (1A446)

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Anti-Mouse WDR45 Monoclonal Antibody (1A446).pdf

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Anti-Mouse WDR45 Monoclonal Antibody (1A446) (MP297025)

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