Anti-MPP5 Polyclonal Antibody (HV348014)

Name: Anti-MPP5 Polyclonal Antibody
Brand: abinScience
SKU: HV348014
Price: 96 USD
Availability: InStock

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SDS

Aperçu

Numéro de catalogue

HV348014

Description

Anti-MPP5 Polyclonal Antibody (HV348014) is a rabbit polyclonal antibody detecting MPP5 in ELISA, IHC, WB. Suitable for Human, Mouse, Dog, Rat, and Pongo abelii.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

Reactivité des espèces

Human, Mouse, Rat

Applications

ELISA, IHC, WB

Espèce hôte

Rabbit

Clonalité

Polyclonal

Isotype

IgG

Immunogène

E. coli - derived recombinant Human MPP5 (Asn455-Arg675).

Cible

PALS1, MAGUK p55 subfamily member 5, MPP5

Purification

Purified by antigen affinity column.

Numéro d'accès

Q8N3R9

Forme

Liquid

Tampon de stockage

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.

Informations d'utilisation du produit

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stabilité et stockage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Contexte

Protein PALS1 (MPP5) is a ~77 kDa protein. Plays a role in tight junction biogenesis and in the establishment of cell polarity in epithelial cells. Also involved in adherens junction biogenesis by ensuring correct localization of the exocyst complex protein EXOC4/SEC8 which allows trafficking of adherens junction structural component CDH1 to the cell surface. Plays a role through its interaction with CDH5 in vascular lumen formation and endothelial membrane polarity. Required during embryonic and postnatal retinal development. Required for the maintenance of cerebellar progenitor cells in an undifferentiated proliferative state, preventing premature differentiation, and is required for cerebellar histogenesis, fissure formation, cerebellar layer organization and cortical development.

1. Wells, CD. et al. (2006) Cell 125, 535-48. PMID: 16678097

2. Li, Y. et al. (2014) Proceedings of the National Academy of Sciences of the United States of America 111, 17444-9. PMID: 25385611

3. Brinkmann, BF. et al. (2016) Molecular biology of the cell 27, 2811-21. PMID: 27466317

4. Carvalho, G. et al. (2011) PloS one 6, e18159. PMID: 21479189

Note

For research use only.

Images

Reférences

Fiche technique

Anti-MPP5 Polyclonal Antibody.pdf

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Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Protéines Recombinantes

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