Anti-MPP5 Polyclonal Antibody (HV348014)

Name: Anti-MPP5 Polyclonal Antibody
Brand: abinScience
SKU: HV348014
Price: 96 USD
Availability: InStock

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Обзор

Каталожный номер

HV348014

Описание

Anti-MPP5 Polyclonal Antibody (HV348014) is a rabbit polyclonal antibody detecting MPP5 in ELISA, IHC, WB. Suitable for Human, Mouse, Dog, Rat, and Pongo abelii.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

Реактивность видов

Human, Mouse, Rat

Применения

ELISA, IHC, WB

Хозяинский вид

Rabbit

Клоональность

Polyclonal

Изотип

IgG

Иммуноген

E. coli - derived recombinant Human MPP5 (Asn455-Arg675).

Цель

PALS1, MAGUK p55 subfamily member 5, MPP5

Очистка

Purified by antigen affinity column.

Номер доступа

Q8N3R9

Форма

Liquid

Буфер хранения

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии.

Информация об использовании продукта

Применение	Разбавление
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Устойчивость и хранение

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Фон

Protein PALS1 (MPP5) is a ~77 kDa protein. Plays a role in tight junction biogenesis and in the establishment of cell polarity in epithelial cells. Also involved in adherens junction biogenesis by ensuring correct localization of the exocyst complex protein EXOC4/SEC8 which allows trafficking of adherens junction structural component CDH1 to the cell surface. Plays a role through its interaction with CDH5 in vascular lumen formation and endothelial membrane polarity. Required during embryonic and postnatal retinal development. Required for the maintenance of cerebellar progenitor cells in an undifferentiated proliferative state, preventing premature differentiation, and is required for cerebellar histogenesis, fissure formation, cerebellar layer organization and cortical development.

1. Wells, CD. et al. (2006) Cell 125, 535-48. PMID: 16678097

2. Li, Y. et al. (2014) Proceedings of the National Academy of Sciences of the United States of America 111, 17444-9. PMID: 25385611

3. Brinkmann, BF. et al. (2016) Molecular biology of the cell 27, 2811-21. PMID: 27466317

4. Carvalho, G. et al. (2011) PloS one 6, e18159. PMID: 21479189

Примечание

For research use only.

Изображения

Ссылки

Даташит

Anti-MPP5 Polyclonal Antibody.pdf

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Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

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