Anti-MRV-1 SigmaNS/S3 Polyclonal Antibody (VK093014)

Name: Anti-MRV-1 SigmaNS/S3 Polyclonal Antibody
Brand: abinScience
SKU: VK093014
Price: 168 USD
Availability: InStock

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概要
イメージ
参考文献
データシート
SDS

概要

カタログ番号

VK093014

説明

Anti-MRV-1 SigmaNS/S3 Polyclonal Antibody (VK093014) is a rabbit polyclonal antibody detecting MRV-1 SigmaNS/S3 in ELISA, IHC, WB. Suitable for Reovirus type 1, Reovirus type 2, and Reovirus type 3.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

種反応性

Mammalian orthoreovirus 1 (MRV1)

アプリケーション

ELISA, IHC, WB

宿主種

Rabbit

クローン性

Polyclonal

アイソタイプ

IgG

免疫原

E. coli - derived recombinant MRV-1 SigmaNS/S3 (Met1-Val366).

ターゲット

sigma-NS protein, S3

エンドトキシンレベル

Please contact with the lab for this information.

精製

Purified by antigen affinity column.

アクセッション番号

P07940, P12002, P03526

形態

Liquid

保存バッファー

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。

製品使用情報

アプリケーション	希釈
ELISA	1:5000-1:20000,IHC:1:50-1:500,WB:1:500-1:2000

安定性と保存

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

背景

Protein sigma-NS (SigmaNS/S3) is a ~41 kDa protein. Protein that binds to ssRNA and participates with protein mu-NS in forming the matrix of viral factories, which are large inclusions in the host cytoplasm where replication intermediates are assembled and viral RNA replication takes place. Plays a role in the inhibition of the integrated stress response (ISR) to escape from host cell translational shutoff. Participates in the disruption of stress granules (SG) through its association with host G3BP1 and mu-NS.

1. Gillian, AL. et al. (1998) Virology 240, 1-11. PMID: 9448684

2. Choudhury, P. et al. (2017) Journal of virology 91. PMID: 28794026

注意事項

For research use only

イメージ

参考文献

データシート

Anti-MRV-1 SigmaNS/S3 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

組換えタンパク質

抗体

アッセイキット

Anti-MRV-1 SigmaNS/S3 Polyclonal Antibody (VK093014)

概要

イメージ

参考文献

データシート

SDS