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Каталожный номерVK093014
Описание
Anti-MRV-1 SigmaNS/S3 Polyclonal Antibody (VK093014) is a rabbit polyclonal antibody detecting MRV-1 SigmaNS/S3 in ELISA, IHC, WB. Suitable for Reovirus type 1, Reovirus type 2, and Reovirus type 3.
Highlights
  • ●Affinity Purified — Minimal background and high purity for reliable results.
  • ●Multi-Application — Validated across multiple applications.
  • ●Multi-Species — Cross-reactive for translational research.
Реактивность видовMammalian orthoreovirus 1 (MRV1)
ПримененияELISA, IHC, WB
Хозяинский видRabbit
КлоональностьPolyclonal
ИзотипIgG
Иммуноген E. coli - derived recombinant MRV-1 SigmaNS/S3 (Met1-Val366).
Цель sigma-NS protein, S3
Уровень эндотоксинов Please contact with the lab for this information.
Очистка Purified by antigen affinity column.
Номер доступа P07940, P12002, P03526
Форма Liquid
Буфер хранения 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии.

Информация об использовании продукта
Применение Разбавление
ELISA 1:5000-1:20000,IHC:1:50-1:500,WB:1:500-1:2000
Устойчивость и хранение Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Фон

Protein sigma-NS (SigmaNS/S3) is a ~41 kDa protein. Protein that binds to ssRNA and participates with protein mu-NS in forming the matrix of viral factories, which are large inclusions in the host cytoplasm where replication intermediates are assembled and viral RNA replication takes place. Plays a role in the inhibition of the integrated stress response (ISR) to escape from host cell translational shutoff. Participates in the disruption of stress granules (SG) through its association with host G3BP1 and mu-NS.

1. Gillian, AL. et al. (1998) Virology 240, 1-11. PMID: 9448684
2. Choudhury, P. et al. (2017) Journal of virology 91. PMID: 28794026
Примечание For research use only
Изображения
Ссылки
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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