

| Numéro de catalogue | VK094044 | ||||
|---|---|---|---|---|---|
| Description |
Anti-MRV-3 Sigma1/S1 Polyclonal Antibody (VK094044) is a rabbit polyclonal antibody detecting MRV-3 Sigma1/S1 in ELISA, IHC, WB. Suitable for Bacillus phage SF6 and Reovirus type 3.
Highlights
|
||||
| Reactivité des espèces | Mammalian orthoreovirus 1 (MRV1) | ||||
| Applications | ELISA, IHC, WB | ||||
| Espèce hôte | Rabbit | ||||
| Clonalité | Polyclonal | ||||
| Isotype | IgG | ||||
| Immunogène | E. coli - derived recombinant MRV-3 Sigma1/S1 (Val170-Thr455). | ||||
| Cible | sigma-1 protein, S1 | ||||
| Niveau d'endotoxines | Please contact with the lab for this information. | ||||
| Pureté | >95% as determined by SDS-PAGE. | ||||
| Purification | Purified by antigen affinity column. | ||||
| Numéro d'accès | P03528, P21270 | ||||
| Forme | Liquid | ||||
| Tampon de stockage | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot. |
||||
| Informations d'utilisation du produit |
| ||||
| Stabilité et stockage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||
| Contexte | Outer capsid protein sigma-1 (Sigma1/S1) is a ~49 kDa protein. Fiber-like molecule of about 30 nm that attaches the virion to the host cell membrane by binding with initial low affinity to sialic acid containing proteins, followed by high-affinity bindingto the entry receptor F11R/JAM-A. The interaction of sigma-1 with F11R is required for NF-kB activation and apoptosis. Binding to both sialic acid and F11R is required to induce maximal levels of apoptosis. 1. Barton, ES. et al. (2001) Cell 104, 441-51. PMID: 11239401 2. Kirchner, E. et al. (2008) PLoS pathogens 4, e1000235. PMID: 19079583 3. Reiter, DM. et al. (2011) PLoS pathogens 7, e1002166. PMID: 21829363 | ||||
| Note | For research use only |
Contactez-nous pour les devis personnalisés, les demandes en gros et tout autre problème.
Courrier : [email protected]
Accès rapide
Contactez-nous
+86-027-65523339
Bâtiment C, No. 666, Rue Shendunsi, Wuhan, 430206, Chine
中文
English
한국어
日本語
Español
Français
Русский