

| Numéro de catalogue | VK094014 | ||||
|---|---|---|---|---|---|
| Description |
Anti-MRV-3 SigmaNS/S3 Polyclonal Antibody (VK094014) is a rabbit polyclonal antibody detecting MRV-3 SigmaNS/S3 in ELISA, IHC, WB. Suitable for Reovirus type 2, Reovirus type 1, and Reovirus type 3.
Highlights
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| Reactivité des espèces | Mammalian orthoreovirus 1 (MRV1) | ||||
| Applications | ELISA, IHC, WB | ||||
| Espèce hôte | Rabbit | ||||
| Clonalité | Polyclonal | ||||
| Isotype | IgG | ||||
| Immunogène | E. coli - derived recombinant MRV-3 SigmaNS/S3 (Met1-Val366). | ||||
| Cible | sigma-NS protein, S3 | ||||
| Niveau d'endotoxines | Please contact with the lab for this information. | ||||
| Pureté | >95% as determined by SDS-PAGE. | ||||
| Purification | Purified by antigen affinity column. | ||||
| Numéro d'accès | P07940, P12002, P03526 | ||||
| Forme | Liquid | ||||
| Tampon de stockage | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot. |
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| Informations d'utilisation du produit |
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| Stabilité et stockage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||
| Contexte | Protein sigma-NS (SigmaNS/S3) is a ~41 kDa protein. Protein that binds to ssRNA and participates with protein mu-NS in forming the matrix of viral factories, which are large inclusions in the host cytoplasm where replication intermediates are assembled and viral RNA replication takes place. Plays a role in the inhibition of the integrated stress response (ISR) to escape from host cell translational shutoff. Participates in the disruption of stress granules (SG) through its association with host G3BP1 and mu-NS. 1. Gillian, AL. et al. (1998) Virology 240, 1-11. PMID: 9448684 2. Choudhury, P. et al. (2017) Journal of virology 91. PMID: 28794026 | ||||
| Note | For research use only |
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