

| Каталожный номер | VK094014 | ||||
|---|---|---|---|---|---|
| Описание |
Anti-MRV-3 SigmaNS/S3 Polyclonal Antibody (VK094014) is a rabbit polyclonal antibody detecting MRV-3 SigmaNS/S3 in ELISA, IHC, WB. Suitable for Reovirus type 2, Reovirus type 1, and Reovirus type 3.
Highlights
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| Реактивность видов | Mammalian orthoreovirus 1 (MRV1) | ||||
| Применения | ELISA, IHC, WB | ||||
| Хозяинский вид | Rabbit | ||||
| Клоональность | Polyclonal | ||||
| Изотип | IgG | ||||
| Иммуноген | E. coli - derived recombinant MRV-3 SigmaNS/S3 (Met1-Val366). | ||||
| Цель | sigma-NS protein, S3 | ||||
| Уровень эндотоксинов | Please contact with the lab for this information. | ||||
| Чистота | >95% as determined by SDS-PAGE. | ||||
| Очистка | Purified by antigen affinity column. | ||||
| Номер доступа | P07940, P12002, P03526 | ||||
| Форма | Liquid | ||||
| Буфер хранения | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии. |
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| Информация об использовании продукта |
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| Устойчивость и хранение | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||
| Фон | Protein sigma-NS (SigmaNS/S3) is a ~41 kDa protein. Protein that binds to ssRNA and participates with protein mu-NS in forming the matrix of viral factories, which are large inclusions in the host cytoplasm where replication intermediates are assembled and viral RNA replication takes place. Plays a role in the inhibition of the integrated stress response (ISR) to escape from host cell translational shutoff. Participates in the disruption of stress granules (SG) through its association with host G3BP1 and mu-NS. 1. Gillian, AL. et al. (1998) Virology 240, 1-11. PMID: 9448684 2. Choudhury, P. et al. (2017) Journal of virology 91. PMID: 28794026 | ||||
| Примечание | For research use only |
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