Anti-MSUN2 Polyclonal Antibody (MC621014)

Name: Anti-MSUN2 Polyclonal Antibody
Brand: abinScience
SKU: MC621014
Price: 168 USD
Availability: InStock

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50ug
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Imágenes
Referencias
Datasheet
SDS

Vista general

Número de catálogo

MC621014

Descripción

Anti-MSUN2 Polyclonal Antibody (MC621014) is a rabbit polyclonal antibody detecting MSUN2 in ELISA, IHC, WB. Suitable for Mouse and Human.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

Reactividad de especies

Human, Mouse

Aplicaciones

ELISA, IHC, WB

Especie huésped

Rabbit

Clonalidad

Polyclonal

Isotipo

IgG

Inmunógeno

E. coli - derived recombinant mouse MSUN2 (Asn45-Ala431).

Objetivo

D13Wsu123e, EC:2.1.1.-, EC:2.1.1.203, Misu, Myc-induced SUN domain-containing protein, NOL1/NOP2/Sun domain family member 2, Nsun2, RNA cytosine C(5)-methyltransferase NSUN2, mRNA cytosine C(5)-methyltransferase, tRNA cytosine C(5)-methyltransferase

Nivel de endotoxinas

Please contact with the lab for this information.

Purificación

Purified by antigen affinity column.

Número de acceso

Q1HFZ0

Forma

Liquid

Buffer de almacenamiento

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.

Información de uso del producto

Aplicación	Dilución
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Estabilidad y almacenamiento

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Fondo

RNA cytosine C(5)-methyltransferase NSUN2 (MSUN2) is a ~85 kDa protein. RNA cytosine C(5)-methyltransferase that methylates cytosine to 5-methylcytosine (m5C) in various RNAs, such as tRNAs, mRNAs and some long non-coding RNAs (lncRNAs). Involved in various processes, such as epidermal stem cell differentiation, testis differentiation and maternal to zygotic transition during early development: acts by increasing protein synthesis; cytosine C(5)-methylation promoting tRNA stability and preventing mRNA decay. Methylates cytosine to 5-methylcytosine (m5C) at positions 34 and 48 of intron-containing tRNA(Leu)(CAA) precursors, and at positions 48, 49 and 50 of tRNA(Gly)(GCC) precursors. tRNA methylation is required generation of RNA fragments derived from tRNAs (tRFs). Also mediates C(5)-methylation of mitochondrial tRNAs.

1. Blanco, S. et al. (2011) PLoS genetics 7, e1002403. PMID: 22144916

2. Hussain, S. et al. (2013) Cell reports 4, 255-61. PMID: 23871666

3. Gkatza, NA. et al. (2019) PLoS biology 17, e3000297. PMID: 31199786

4. Tuorto, F. et al. (2012) Nature structural & molecular biology 19, 900-5. PMID: 22885326

5. Hussain, S. et al. (2013) Molecular and cellular biology 33, 1561-70. PMID: 23401851

6. Van Haute, L. et al. (2019) Nucleic acids research 47, 8720-8733. PMID: 31276587

Nota

For research use only

Imágenes

Referencias

Datasheet

Anti-MSUN2 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Proteínas Recombinantes

Anticuerpos

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