

| Numéro de catalogue | HF713014 | ||||||||
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| Description |
Anti-MYC Polyclonal Antibody (HF713014) is a rabbit polyclonal antibody detecting MYC in ELISA, IHC, WB. Suitable for Human, Mouse, Cat, Rat, and Bovine.
Highlights
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| Reactivité des espèces | Human, Mouse, Rat | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Espèce hôte | Rabbit | ||||||||
| Clonalité | Polyclonal | ||||||||
| Isotype | IgG | ||||||||
| Immunogène | E. coli - derived recombinant Human MYC (Glu351-Ser437). | ||||||||
| Cible | Proto-oncogene c-Myc, BHLHE39, MYC, Myc proto-oncogene protein, bHLHe39, Transcription factor p64, Class E basic helix-loop-helix protein 39 | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Numéro d'accès | P01106 | ||||||||
| Forme | Liquid | ||||||||
| Tampon de stockage | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot. |
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| Informations d'utilisation du produit |
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| Stabilité et stockage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Contexte | Myc proto-oncogene protein is a ~50 kDa protein. Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. Binds to the VEGFA promoter, promoting VEGFA production and subsequent sprouting angiogenesis. Regulator of somatic reprogramming, controls self-renewal of embryonic stem cells. Functions with TAF6L to activate target gene expression through RNA polymerase II pause release. 1. Shi, Y. et al. (2014) eLife 3, e02349. PMID: 24940000 2. Kim, JY. et al. (2015) The American journal of pathology 185, 2061-8. PMID: 25956029 3. David, CJ. et al. (2010) Nature 463, 364-8. PMID: 20010808 | ||||||||
| Note | For research use only. |




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