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| カタログ番号 | HF713024 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 説明 |
Anti-MYC Polyclonal Antibody (HF713024) is a rabbit polyclonal antibody detecting MYC in ELISA, IHC, WB. Suitable for Human, Mouse, and Rat.
Highlights
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| 種反応性 | Human | ||||||||
| アプリケーション | ELISA, IHC, WB | ||||||||
| 宿主種 | Rabbit | ||||||||
| クローン性 | Polyclonal | ||||||||
| アイソタイプ | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Human MYC (Met1-Ala453). | ||||||||
| ターゲット | Proto-oncogene c-Myc, BHLHE39, MYC, Myc proto-oncogene protein, bHLHe39, Transcription factor p64, Class E basic helix-loop-helix protein 39 | ||||||||
| 精製 | Purified by antigen affinity column. | ||||||||
| アクセッション番号 | P01106 | ||||||||
| 形態 | Liquid | ||||||||
| 保存バッファー | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Myc proto-oncogene protein is a ~50 kDa protein. Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. Binds to the VEGFA promoter, promoting VEGFA production and subsequent sprouting angiogenesis. Regulator of somatic reprogramming, controls self-renewal of embryonic stem cells. Functions with TAF6L to activate target gene expression through RNA polymerase II pause release. 1. Shi, Y. et al. (2014) eLife 3, e02349. PMID: 24940000 2. Kim, JY. et al. (2015) The American journal of pathology 185, 2061-8. PMID: 25956029 3. David, CJ. et al. (2010) Nature 463, 364-8. PMID: 20010808 | ||||||||
| 注意事項 | For research use only. |
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