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Anti-Mycobacterium tuberculosis katG Recombinant Antibody (SAA2165) (JN041013)

Anti-Mycobacterium tuberculosis katG Recombinant Antibody (SAA2165)
Anti-Mycobacterium tuberculosis katG Recombinant Antibody (SAA2165)
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概要
カタログ番号JN041013
種反応性Mycobacterium tuberculosis
アプリケーションELISA, WB
宿主種Human
クローン性Monoclonal
アイソタイプIgG1
クローンIDSAA2165
ターゲット Catalase-peroxidase, CP, 1.11.1.21, Peroxidase/catalase, katG, Rv1908c, MTCY180.10
エンドトキシンレベル Please contact with the lab for this information.
純度 >95% as determined by SDS-PAGE.
精製 Protein A/G purified from cell culture supernatant.
アクセッション番号 P9WIE5
RRID Anti-Mycobacterium tuberculosis katG Antibody (SAA2165) (abinScience Cat# JN041013, RRID:AB_3729533)
形態 Liquid
保存バッファー 0.01M PBS pH 7.4

データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。

製品使用情報
アプリケーション 希釈
ELISA 1:2000-1:20000
WB 1:500-1:2000
安定性と保存 Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
背景

Catalase-peroxidase (katG) is a ~80 kDa protein. Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity, oxidizing various electron donors including NADP(H). Protects M.tuberculosis against toxic reactive oxygen species (ROS) including hydrogen peroxide as well as organic peroxides and thus contributes to its survival within host macrophages by countering the phagocyte oxidative burst. Also displays efficient peroxynitritase activity, which may help the bacterium to persist in macrophages.

1. Singh, R. et al. (2008) Archives of biochemistry and biophysics 471, 207-14. PMID: 18178143
2. Johnsson, K. et al. (1997) The Journal of biological chemistry 272, 2834-40. PMID: 9006925
3. Ng, VH. et al. (2004) Molecular microbiology 52, 1291-302. PMID: 15165233
4. Sherman, DR. et al. (1996) Science (New York, N.Y.) 272, 1641-3. PMID: 8658136
5. Wengenack, NL. et al. (1999) Biochemical and biophysical research communications 256, 485-7. PMID: 10080924
注意事項 For research use only.
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  • Anti-Mycobacterium tuberculosis katG Recombinant Antibody (SAA2165)

    SDS-PAGE

    SDS-PAGE for Anti-Mycobacterium tuberculosis katG Recombinant Antibody (SAA2165)

参考文献
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
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Working Solution
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