

| Numéro de catalogue | HS792014 | ||||||||
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| Description |
Anti-MYLK Polyclonal Antibody (HS792014) is a rabbit polyclonal antibody detecting MYLK in ELISA, IHC, WB. Suitable for Human, Mouse, Bovine, and Ovis aries.
Highlights
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| Reactivité des espèces | Human, Mouse | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Espèce hôte | Rabbit | ||||||||
| Clonalité | Polyclonal | ||||||||
| Isotype | IgG | ||||||||
| Immunogène | E. coli - derived recombinant Human MYLK (Thr1748-Glu1914). | ||||||||
| Cible | MLCK1, smMLCK, MYLK1, KRP, Kinase-related protein, MLCK, MYLK, Myosin light chain kinase, smooth muscle, Telokin | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Numéro d'accès | Q15746 | ||||||||
| Forme | Liquid | ||||||||
| Tampon de stockage | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot. |
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| Informations d'utilisation du produit |
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| Stabilité et stockage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Contexte | Myosin light chain kinase, smooth muscle (MYLK) is a ~210 kDa protein. Calcium/calmodulin-dependent myosin light chain kinase implicated in smooth muscle contraction via phosphorylation of myosin light chains (MLC). Also regulates actin-myosin interaction through a non-kinase activity. Phosphorylates PTK2B/PYK2 and myosin light-chains. Involved in the inflammatory response (e.g. apoptosis, vascular permeability, leukocyte diapedesis), cell motility and morphology, airway hyperreactivity and other activities relevant to asthma. | ||||||||
| Note | For research use only. |
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