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| カタログ番号 | HC094014 | ||||||||
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| 説明 |
Anti-NACA Polyclonal Antibody (HC094014) is a rabbit polyclonal antibody detecting NACA in ELISA, IHC, WB. Suitable for Bovine, Mouse, Human, Frog, and Zebrafish.
Highlights
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| 種反応性 | Human, Mouse | ||||||||
| アプリケーション | ELISA, IHC, WB | ||||||||
| 宿主種 | Rabbit | ||||||||
| クローン性 | Polyclonal | ||||||||
| アイソタイプ | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant NACA (Pro63-Met215). | ||||||||
| ターゲット | Nascent polypeptide-associated complex subunit alpha, NAC-alpha, Alpha-NAC, Hom s 2, NACA | ||||||||
| エンドトキシンレベル | Please contact with the lab for this information. | ||||||||
| 精製 | Purified by antigen affinity column. | ||||||||
| アクセッション番号 | Q5E9A1, Q60817, P70670, E9PAV3, Q13765, Q6IP73, Q8JIU7, Q9H009, Q9BZK3 | ||||||||
| 形態 | Liquid | ||||||||
| 保存バッファー | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Nascent polypeptide-associated complex subunit alpha is a ~23 kDa protein. Prevents inappropriate targeting of non-secretory polypeptides to the endoplasmic reticulum (ER). Binds to nascent polypeptide chains as they emerge from the ribosome and blocks their interaction with the signal recognition particle (SRP), which normally targets nascent secretory peptides to the ER. Also reduces the inherent affinity of ribosomes for protein translocation sites in the ER membrane (M sites). May act as a specific coactivator for JUN, binding to DNA and stabilizing the interaction of JUN homodimers with target gene promoters. | ||||||||
| 注意事項 | For research use only |
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