Anti-NAMPT Polyclonal Antibody (HW363014)

Name: Anti-NAMPT Polyclonal Antibody
Brand: abinScience
SKU: HW363014
Price: 168 USD
Availability: InStock

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Especificación:

50ug
100ug

Número:

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Datasheet
SDS

Vista general

Número de catálogo

HW363014

Descripción

Anti-NAMPT Polyclonal Antibody (HW363014) is a rabbit polyclonal antibody detecting NAMPT in ELISA, IHC, WB. Suitable for Human, Mouse, Rat, and Pig.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

Reactividad de especies

Human, Mouse, Rat

Aplicaciones

ELISA, IHC, WB

Especie huésped

Rabbit

Clonalidad

Polyclonal

Isotipo

IgG

Inmunógeno

E. coli - derived recombinant Human NAMPT (Met1-His491).

Objetivo

NAMPT, Pre-B-cell colony-enhancing factor 1, NAmPRTase, Pre-B cell-enhancing factor, Nicotinamide phosphoribosyltransferase, Visfatin, PBEF, PBEF1, Nampt

Purificación

Purified by antigen affinity column.

Número de acceso

P43490

Forma

Liquid

Buffer de almacenamiento

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.

Información de uso del producto

Aplicación	Dilución
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Estabilidad y almacenamiento

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Fondo

Nicotinamide phosphoribosyltransferase (NAMPT) is a ~55 kDa protein. Catalyzes the condensation of nicotinamide with 5-phosphoribosyl-1-pyrophosphate to yield nicotinamide mononucleotide, an intermediate in the biosynthesis of NAD. It is the rate limiting component in the mammalian NAD biosynthesis pathway. The secreted form behaves both as a cytokine with immunomodulating properties and an adipokine with anti-diabetic properties, it has no enzymatic activity, partly because of lack of activation by ATP, which has a low level in extracellular space and plasma. Plays a role in the modulation of circadian clock function. NAMPT-dependent oscillatory production of NAD regulates oscillation of clock target gene expression by releasing the core clock component: CLOCK-BMAL1 heterodimer from NAD-dependent SIRT1-mediated suppression.

Nota

For research use only.

Imágenes

Referencias

Datasheet