Anti-NCAPH2 Polyclonal Antibody (HC060014)

Name: Anti-NCAPH2 Polyclonal Antibody
Brand: abinScience
SKU: HC060014
Price: 96 USD
Availability: InStock

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20ug
50ug
100ug

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Reférences
Fiche technique
SDS

Aperçu

Numéro de catalogue

HC060014

Description

Anti-NCAPH2 Polyclonal Antibody (HC060014) is a rabbit polyclonal antibody detecting Condensin-2 complex subunit H2; Chromosome-associated protein H2; hCAP-H2; Kleisin-beta; Non-SMC condensin II complex subunit H2; NCAPH2; CAPH2 in ELISA, IHC, WB. Suitable for Human, Mouse, and Rat.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

Reactivité des espèces

Human, Mouse

Applications

ELISA, IHC, WB

Espèce hôte

Rabbit

Clonalité

Polyclonal

Isotype

IgG

Immunogène

E. coli - derived recombinant human NCAPH2 (Ser464-Pro605).

Cible

Condensin-2 complex subunit H2; Chromosome-associated protein H2; hCAP-H2; Kleisin-beta; Non-SMC condensin II complex subunit H2; NCAPH2; CAPH2

Niveau d'endotoxines

Please contact with the lab for this information.

Purification

Purified by antigen affinity column.

Numéro d'accès

Q6IBW4, Q8BSP2, Q4V8I2

Forme

Liquid

Tampon de stockage

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.

Informations d'utilisation du produit

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stabilité et stockage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Contexte

Condensin-2 complex subunit H2 (NCAPH2) is a ~68 kDa protein. Regulatory subunit of the condensin-2 complex, a complex that seems to provide chromosomes with an additional level of organization and rigidity and in establishing mitotic chromosome architecture. May promote the resolution of double-strand DNA catenanes (intertwines) between sister chromatids. Condensin-mediated compaction likely increases tension in catenated sister chromatids, providing directionality for type II topoisomerase-mediated strand exchanges toward chromatid decatenation. Required for decatenation of chromatin bridges at anaphase. Early in neurogenesis, may play an essential role to ensure accurate mitotic chromosome condensation in neuron stem cells, ultimately affecting neuron pool and cortex size.

1. Ono, T. et al. (2003) Cell 115, 109-21. PMID: 14532007

Note

For research use only

Images

Western blot

Western blot analysis was performed using anti-NCAPH2 polyclonal antibody at 1ug/mL on various samples.
Lane 1: Mouse brain lysate
Lane 2: Rat brain lysate

Reférences

Fiche technique

Anti-NCAPH2 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Protéines Recombinantes

Anticorps

Kits d'Essai

Anti-NCAPH2 Polyclonal Antibody (HC060014)

Aperçu

Images

Reférences

Fiche technique

SDS