Anti-NCAPH2 Polyclonal Antibody (HC060014)

Name: Anti-NCAPH2 Polyclonal Antibody
Brand: abinScience
SKU: HC060014
Price: 96 USD
Availability: InStock

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Каталожный номер

HC060014

Описание

Anti-NCAPH2 Polyclonal Antibody (HC060014) is a rabbit polyclonal antibody detecting Condensin-2 complex subunit H2; Chromosome-associated protein H2; hCAP-H2; Kleisin-beta; Non-SMC condensin II complex subunit H2; NCAPH2; CAPH2 in ELISA, IHC, WB. Suitable for Human, Mouse, and Rat.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

Реактивность видов

Human, Mouse

Применения

ELISA, IHC, WB

Хозяинский вид

Rabbit

Клоональность

Polyclonal

Изотип

IgG

Иммуноген

E. coli - derived recombinant human NCAPH2 (Ser464-Pro605).

Цель

Condensin-2 complex subunit H2; Chromosome-associated protein H2; hCAP-H2; Kleisin-beta; Non-SMC condensin II complex subunit H2; NCAPH2; CAPH2

Уровень эндотоксинов

Please contact with the lab for this information.

Очистка

Purified by antigen affinity column.

Номер доступа

Q6IBW4, Q8BSP2, Q4V8I2

Форма

Liquid

Буфер хранения

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии.

Информация об использовании продукта

Применение	Разбавление
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Устойчивость и хранение

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Фон

Condensin-2 complex subunit H2 (NCAPH2) is a ~68 kDa protein. Regulatory subunit of the condensin-2 complex, a complex that seems to provide chromosomes with an additional level of organization and rigidity and in establishing mitotic chromosome architecture. May promote the resolution of double-strand DNA catenanes (intertwines) between sister chromatids. Condensin-mediated compaction likely increases tension in catenated sister chromatids, providing directionality for type II topoisomerase-mediated strand exchanges toward chromatid decatenation. Required for decatenation of chromatin bridges at anaphase. Early in neurogenesis, may play an essential role to ensure accurate mitotic chromosome condensation in neuron stem cells, ultimately affecting neuron pool and cortex size.

1. Ono, T. et al. (2003) Cell 115, 109-21. PMID: 14532007

Примечание

For research use only

Изображения

Western blot

Western blot analysis was performed using anti-NCAPH2 polyclonal antibody at 1ug/mL on various samples.
Lane 1: Mouse brain lysate
Lane 2: Rat brain lysate

Ссылки

Даташит

Anti-NCAPH2 Polyclonal Antibody.pdf

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Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Рекомбинантные Белки

Антитела

Наборы для анализа

Anti-NCAPH2 Polyclonal Antibody (HC060014)

Обзор

Изображения

Ссылки

Даташит

SDS