Anti-NCSTN Polyclonal Antibody (HV481014)

Name: Anti-NCSTN Polyclonal Antibody
Brand: abinScience
SKU: HV481014
Price: 168 USD
Availability: InStock

データシート製品共有情報コピー

価格(USD): --

スペック:

50ug
100ug

数量:

お問い合わせ

概要
イメージ
参考文献
データシート
SDS

概要

カタログ番号

HV481014

説明

Anti-NCSTN Polyclonal Antibody (HV481014) is a rabbit polyclonal antibody detecting NCSTN in ELISA, IHC, WB. Suitable for Human, Mouse, and Rat.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

種反応性

Human

アプリケーション

ELISA, IHC, WB

宿主種

Rabbit

クローン性

Polyclonal

アイソタイプ

IgG

免疫原

E. coli - derived recombinant Human NCSTN (Gln420-Asp655).

ターゲット

KIAA0253, Nicastrin, NCSTN

精製

Purified by antigen affinity column.

アクセッション番号

Q92542

形態

Liquid

保存バッファー

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。

製品使用情報

アプリケーション	希釈
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

安定性と保存

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

背景

Nicastrin (NCSTN) is a ~78 kDa protein. Essential subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP (amyloid-beta precursor protein). The gamma-secretase complex plays a role in Notch and Wnt signaling cascades and regulation of downstream processes via its role in processing key regulatory proteins, and by regulating cytosolic CTNNB1 levels.

1. Yu, G. et al. (2000) Nature 407, 48-54. PMID: 10993067

2. Edbauer, D. et al. (2003) Nature cell biology 5, 486-8. PMID: 12679784

3. Lu, P. et al. (2014) Nature 512, 166-170. PMID: 25043039

4. Bai, XC. et al. (2015) Nature 525, 212-217. PMID: 26280335

5. Yang, G. et al. (2019) Nature 565, 192-197. PMID: 30598546

6. Zhou, R. et al. (2019) Science (New York, N.Y.) 363. PMID: 30630874

注意事項

For research use only.

イメージ

参考文献

データシート

Anti-NCSTN Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

組換えタンパク質

抗体

アッセイキット

Anti-NCSTN Polyclonal Antibody (HV481014)

概要

イメージ

参考文献

データシート

SDS