

| Numéro de catalogue | HV016014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Description |
Anti-NDNF Polyclonal Antibody (HV016014) is a rabbit polyclonal antibody detecting NDNF in ELISA, IHC, WB. Suitable for Human and Mouse.
Highlights
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| Reactivité des espèces | Human | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Espèce hôte | Rabbit | ||||||||
| Clonalité | Polyclonal | ||||||||
| Isotype | IgG | ||||||||
| Immunogène | E. coli - derived recombinant Human NDNF (Met238-Phe331). | ||||||||
| Cible | NDNF, C4orf31, Protein NDNF, Neuron-derived neurotrophic factor | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Numéro d'accès | Q8TB73 | ||||||||
| Forme | Liquid | ||||||||
| Tampon de stockage | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot. |
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| Informations d'utilisation du produit |
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| Stabilité et stockage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Contexte | Protein NDNF is a ~64 kDa protein. Secretory protein that plays a role in various cellular processes. Acts as a chemorepellent acting on gonadotropin-releasing hormone (GnRH) expressing neurons regulating their migration to the hypothalamus. Also promotes neuron migration, growth and survival as well as neurite outgrowth and is involved in the development of the olfactory system. May also act through the regulation of growth factors activity and downstream signaling. Also regulates extracellular matrix assembly and cell adhesiveness. 1. Kuang, XL. et al. (2010) BMC neuroscience 11, 137. PMID: 20969804 2. Ohashi, K. et al. (2014) The Journal of biological chemistry 289, 14132-44. PMID: 24706764 3. Messina, A. et al. (2020) American journal of human genetics 106, 58-70. PMID: 31883645 | ||||||||
| Note | For research use only. |
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