

| Каталожный номер | HT454014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Описание |
Anti-NDUFAB1 Polyclonal Antibody (HT454014) is a rabbit polyclonal antibody detecting NDUFAB1 in ELISA, IHC, WB. Suitable for Human, Pan troglodytes, and Pongo pygmaeus.
Highlights
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| Реактивность видов | Human | ||||||||
| Применения | ELISA, IHC, WB | ||||||||
| Хозяинский вид | Rabbit | ||||||||
| Клоональность | Polyclonal | ||||||||
| Изотип | IgG | ||||||||
| Иммуноген | E. coli - derived recombinant Human NDUFAB1 (Val5-Glu129). | ||||||||
| Цель | ACP, CI-SDAP, NADH-ubiquinone oxidoreductase 9.6 kDa subunit, Acyl carrier protein, mitochondrial, NDUFAB1 | ||||||||
| Уровень эндотоксинов | Please contact with the lab for this information. | ||||||||
| Очистка | Purified by antigen affinity column. | ||||||||
| Номер доступа | O14561 | ||||||||
| Форма | Liquid | ||||||||
| Буфер хранения | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии. |
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| Информация об использовании продукта |
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| Устойчивость и хранение | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Фон | Acyl carrier protein, mitochondrial (NDUFAB1) is a ~17 kDa protein. Carrier of the growing fatty acid chain in fatty acid biosynthesis. Accessory and non-catalytic subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), which functions in the transfer of electrons from NADH to the respiratory chain. Accessory protein, of the core iron-sulfur cluster (ISC) assembly complex, that regulates, in association with LYRM4, the stability and the cysteine desulfurase activity of NFS1 and participates in the [2Fe-2S] clusters assembly on the scaffolding protein ISCU. The core iron-sulfur cluster (ISC) assembly complex is involved in the de novo synthesis of a [2Fe-2S] cluster, the first step of the mitochondrial iron-sulfur protein biogenesis. This process is initiated by the cysteine desulfurase complex (NFS1:LYRM4:NDUFAB1) that produces persulfide which is delivered on the scaffold protein ISCU in a FXN-dependent manner. 1. Stroud, DA. et al. (2016) Nature 538, 123-126. PMID: 27626371 2. Herrera, MG. et al. (2019) Biochemistry 58, 4596-4609. PMID: 31664822 | ||||||||
| Примечание | For research use only. |
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