Anti-Neisseria meningitidis FHBP Recombinant Antibody (1A12) (JN824013)

Name: Anti-Neisseria meningitidis FHBP Recombinant Antibody (1A12)
Brand: abinScience
SKU: JN824013
Price: 126 USD
Availability: InStock

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Precio(USD):

Especificación:

20ug
50ug
100ug
1mg

Número:

Contáctenos

Vista general
Imágenes
Referencias
Datasheet
SDS

Vista general

Número de catálogo

JN824013

Reactividad de especies

Neisseria meningitidis

Aplicaciones

ELISA

Especie huésped

Mouse

Clonalidad

Monoclonal

Isotipo

IgG2a

ID de clon

1A12

Objetivo

Factor H binding protein, fHbp, Genome-derived Neisseria antigen 1870, GNA1870, Lipoprotein 2086, LP2086, fhbP, NMB1870

Nivel de endotoxinas

Please contact with the lab for this information.

Pureza

>95% as determined by SDS-PAGE.

Purificación

Protein A/G purified from cell culture supernatant.

Número de acceso

Q9JXV4

RRID

Anti-Neisseria meningitidis FHBP Antibody (1A12) (abinScience Cat# JN824013, RRID:AB_3729061)
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Forma

Liquid

Buffer de almacenamiento

0.01M PBS pH 7.4

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.

Información de uso del producto

Aplicación	Dilución
ELISA	1:2000-1:20000

Estabilidad y almacenamiento

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Fondo

Factor H binding protein (FHBP) is a ~28 kDa protein. A bacterial surface lipoprotein that binds host (human) complement factor H (fH, gene CFH), binding contributes to the avoidance of complement-mediated lysis by N.meningitidis. Binding of fH to the bacteria surface is independent of bacterial sialic acid moieties. fH binding affinity is high enough that it may sequester plasma fH, depleting its circulating levels and de-regulating complement in the host (Probable). This protein induces high levels of bactericidal antibodies in mice.

1. Schneider, MC. et al. (2006) Journal of immunology (Baltimore, Md. : 1950) 176, 7566-75. PMID: 16751403

2. Masignani, V. et al. (2003) The Journal of experimental medicine 197, 789-99. PMID: 12642606

3. Fletcher, LD. et al. (2004) Infection and immunity 72, 2088-100. PMID: 15039331

4. Giuliani, MM. et al. (2005) Infection and immunity 73, 1151-60. PMID: 15664958

5. Scarselli, M. et al. (2011) Science translational medicine 3, 91ra62. PMID: 21753121

6. Johnson, S. et al. (2012) PLoS pathogens 8, e1002981. PMID: 23133374

Nota

For research use only.

Imágenes

SDS-PAGE

SDS-PAGE for Anti-Neisseria meningitidis FHBP Antibody (1A12)

Referencias

Datasheet

Anti-Neisseria meningitidis FHBP Recombinant Antibody (1A12).pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Proteínas Recombinantes

Anticuerpos

Kits de Ensayo