

| Numéro de catalogue | HS885014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Description |
Anti-NFKBIB Polyclonal Antibody (HS885014) is a rabbit polyclonal antibody detecting NFKBIB in ELISA, IHC, WB. Suitable for Human.
Highlights
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| Reactivité des espèces | Human | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Espèce hôte | Rabbit | ||||||||
| Clonalité | Polyclonal | ||||||||
| Isotype | IgG | ||||||||
| Immunogène | E. coli - derived recombinant Human NFKBIB (Glu85-His332). | ||||||||
| Cible | IKBB, IkB-beta, TRIP9, TRIP-9, IkappaBbeta, I-kappa-B-beta, IkB-B, NFKBIB, NF-kappa-B inhibitor beta, TR-interacting protein 9, NF-kappa-BIB, Thyroid receptor-interacting protein 9 | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Numéro d'accès | Q15653 | ||||||||
| Forme | Liquid | ||||||||
| Tampon de stockage | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot. |
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| Informations d'utilisation du produit |
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| Stabilité et stockage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Contexte | NF-kappa-B inhibitor beta (NFKBIB) is a ~37 kDa protein. Inhibits NF-kappa-B by complexing with and trapping it in the cytoplasm. However, the unphosphorylated form resynthesized after cell stimulation is able to bind NF-kappa-B allowing its transport to the nucleus and protecting it to further NFKBIA-dependent inactivation. Association with inhibitor kappa B-interacting NKIRAS1 and NKIRAS2 prevent its phosphorylation rendering it more resistant to degradation, explaining its slower degradation. | ||||||||
| Note | For research use only. |
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