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| カタログ番号 | HS885014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 説明 |
Anti-NFKBIB Polyclonal Antibody (HS885014) is a rabbit polyclonal antibody detecting NFKBIB in ELISA, IHC, WB. Suitable for Human.
Highlights
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| 種反応性 | Human | ||||||||
| アプリケーション | ELISA, IHC, WB | ||||||||
| 宿主種 | Rabbit | ||||||||
| クローン性 | Polyclonal | ||||||||
| アイソタイプ | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Human NFKBIB (Glu85-His332). | ||||||||
| ターゲット | IKBB, IkB-beta, TRIP9, TRIP-9, IkappaBbeta, I-kappa-B-beta, IkB-B, NFKBIB, NF-kappa-B inhibitor beta, TR-interacting protein 9, NF-kappa-BIB, Thyroid receptor-interacting protein 9 | ||||||||
| 精製 | Purified by antigen affinity column. | ||||||||
| アクセッション番号 | Q15653 | ||||||||
| 形態 | Liquid | ||||||||
| 保存バッファー | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | NF-kappa-B inhibitor beta (NFKBIB) is a ~37 kDa protein. Inhibits NF-kappa-B by complexing with and trapping it in the cytoplasm. However, the unphosphorylated form resynthesized after cell stimulation is able to bind NF-kappa-B allowing its transport to the nucleus and protecting it to further NFKBIA-dependent inactivation. Association with inhibitor kappa B-interacting NKIRAS1 and NKIRAS2 prevent its phosphorylation rendering it more resistant to degradation, explaining its slower degradation. | ||||||||
| 注意事項 | For research use only. |
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