

| Numéro de catalogue | HT244014 | ||||||||
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| Description |
Anti-NFKBIE Polyclonal Antibody (HT244014) is a rabbit polyclonal antibody detecting NFKBIE in ELISA, IHC, WB. Suitable for Human.
Highlights
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| Reactivité des espèces | Human | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Espèce hôte | Rabbit | ||||||||
| Clonalité | Polyclonal | ||||||||
| Isotype | IgG | ||||||||
| Immunogène | E. coli - derived recombinant Human NFKBIE (Arg207-Pro440). | ||||||||
| Cible | IkB-E, IKBE, IkappaBepsilon, I-kappa-B-epsilon, IkB-epsilon, NFKBIE, NF-kappa-B inhibitor epsilon, NF-kappa-BIE | ||||||||
| Niveau d'endotoxines | Please contact with the lab for this information. | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Numéro d'accès | O00221 | ||||||||
| Forme | Liquid | ||||||||
| Tampon de stockage | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot. |
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| Informations d'utilisation du produit |
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| Stabilité et stockage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Contexte | NF-kappa-B inhibitor epsilon (NFKBIE) is a ~52 kDa protein. Sequesters NF-kappa-B transcription factor complexes in the cytoplasm, thereby inhibiting their activity. Sequestered complexes include NFKB1-RELA (p50-p65) and NFKB1-REL (p50-c-Rel) complexes. Limits B-cell activation in response to pathogens, and also plays an important role in B-cell development. 1. Li, Z. et al. (1997) Molecular and cellular biology 17, 6184-90. PMID: 9315679 2. Whiteside, ST. et al. (1997) The EMBO journal 16, 1413-26. PMID: 9135156 | ||||||||
| Note | For research use only. |
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