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| カタログ番号 | HT244014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 説明 |
Anti-NFKBIE Polyclonal Antibody (HT244014) is a rabbit polyclonal antibody detecting NFKBIE in ELISA, IHC, WB. Suitable for Human.
Highlights
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| 種反応性 | Human | ||||||||
| アプリケーション | ELISA, IHC, WB | ||||||||
| 宿主種 | Rabbit | ||||||||
| クローン性 | Polyclonal | ||||||||
| アイソタイプ | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Human NFKBIE (Arg207-Pro440). | ||||||||
| ターゲット | IkB-E, IKBE, IkappaBepsilon, I-kappa-B-epsilon, IkB-epsilon, NFKBIE, NF-kappa-B inhibitor epsilon, NF-kappa-BIE | ||||||||
| エンドトキシンレベル | Please contact with the lab for this information. | ||||||||
| 精製 | Purified by antigen affinity column. | ||||||||
| アクセッション番号 | O00221 | ||||||||
| 形態 | Liquid | ||||||||
| 保存バッファー | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | NF-kappa-B inhibitor epsilon (NFKBIE) is a ~52 kDa protein. Sequesters NF-kappa-B transcription factor complexes in the cytoplasm, thereby inhibiting their activity. Sequestered complexes include NFKB1-RELA (p50-p65) and NFKB1-REL (p50-c-Rel) complexes. Limits B-cell activation in response to pathogens, and also plays an important role in B-cell development. 1. Li, Z. et al. (1997) Molecular and cellular biology 17, 6184-90. PMID: 9315679 2. Whiteside, ST. et al. (1997) The EMBO journal 16, 1413-26. PMID: 9135156 | ||||||||
| 注意事項 | For research use only. |
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