

| Numéro de catalogue | VK408014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Description |
Anti-Nipah virus M/Protein M Polyclonal Antibody (VK408014) is a rabbit polyclonal antibody detecting Protein M in ELISA, IHC, WB. Suitable for Nipah virus.
Highlights
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| Reactivité des espèces | Nipah virus (NiV) | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Espèce hôte | Rabbit | ||||||||
| Clonalité | Polyclonal | ||||||||
| Isotype | IgG | ||||||||
| Immunogène | E. coli - derived recombinant Nipah virus M/Protein M (Met1-Gly352). | ||||||||
| Cible | Matrix protein, Protein M, M | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Numéro d'accès | Q9IK90 | ||||||||
| Forme | Liquid | ||||||||
| Tampon de stockage | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot. |
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| Informations d'utilisation du produit |
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| Stabilité et stockage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Contexte | Matrix protein (Protein M) is a ~39 kDa protein. Plays a crucial role in virion assembly and budding. Forms a shell at the inner face of the plasma membrane. Transits through the host nucleus before gaining the functional ability to localize and bud from the plasma membrane. Mediates together with fusion protein the incorporation of the glycoprotein to the viral particles. Also participates in the inhibition of the host interferon type I antiviral response by interacting with and thereby inhibiting host TRIM6. 1. Ciancanelli, MJ. et al. (2006) Journal of virology 80, 12070-8. PMID: 17005661 2. Patch, JR. et al. (2007) Virology journal 4, 1. PMID: 17204159 3. Patch, JR. et al. (2008) Virology journal 5, 137. PMID: 19000317 4. Wang, YE. et al. (2010) PLoS pathogens 6, e1001186. PMID: 21085610 5. Johnston, GP. et al. (2017) Journal of virology 91. PMID: 28250132 6. Bharaj, P. et al. (2016) PLoS pathogens 12, e1005880. PMID: 27622505 | ||||||||
| Note | For research use only. |



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