

| Numéro de catalogue | VK441024 | ||||
|---|---|---|---|---|---|
| Description |
Anti-Norovirus 3CLpro Polyclonal Antibody (VK441024) is a rabbit polyclonal antibody detecting Norovirus 3CLpro in ELISA, IHC, WB. Suitable for Norovirus and Southampton virus.
Highlights
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| Reactivité des espèces | Norwalk virus (NoV) | ||||
| Applications | ELISA, IHC, WB | ||||
| Espèce hôte | Rabbit | ||||
| Clonalité | Polyclonal | ||||
| Isotype | IgG | ||||
| Immunogène | E. coli - derived recombinant Norovirus 3CLpro (Ala1101-Glu1281). | ||||
| Cible | Chymotrypsin-like cysteine proteinase, Chymotrypsin-like cysteine proteinase | ||||
| Niveau d'endotoxines | Please contact with the lab for this information. | ||||
| Purification | Purified by antigen affinity column. | ||||
| Numéro d'accès | Q83883, Q04544 | ||||
| Forme | Liquid | ||||
| Tampon de stockage | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot. |
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| Informations d'utilisation du produit |
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| Stabilité et stockage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||
| Contexte | Genome polyprotein (3CLpro) is a ~198 kDa protein. Induces the proliferation of the host smooth ER membranes forming long tubular structures. These remodeled membranes probably form the viral factories that contain the replication complex. Induces the disassembly of host Golgi. May play a role in viral replication by interacting with host VAPA, a vesicle-associated membrane protein that plays a role in SNARE-mediated vesicle fusion. This interaction may target replication complex to intracellular membranes (Probable). 1. Fernandez-Vega, V. et al. (2004) Journal of virology 78, 4827-37. PMID: 15078964 | ||||
| Note | For research use only |
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