Please ensure Javascript is enabled for purposes of website accessibility
Contáctenos Contáctenos
ES
Inicio > Productos > Anticuerpos > Anticuerpos Primarios

Anti-NOTCH2NLA Polyclonal Antibody (HV351014)

Datasheet Compartir producto Copiar información
Precio(USD):
Especificación:
  • 50ug
  • 100ug
Número:
Contáctenos

  • Vista general

  • Imágenes

  • Referencias

  • Datasheet

  • SDS

Vista general
Número de catálogoHV351014
Descripción
Anti-NOTCH2NLA Polyclonal Antibody (HV351014) is a rabbit polyclonal antibody detecting NOTCH2NLA in ELISA, IHC, WB. Suitable for Human, Mouse, and Rat.
Highlights
  • ●Affinity Purified — Minimal background and high purity for reliable results.
  • ●Multi-Application — Validated across multiple applications.
  • ●Multi-Species — Cross-reactive for translational research.
Reactividad de especiesHuman
AplicacionesELISA, IHC, WB
Especie huéspedRabbit
ClonalidadPolyclonal
IsotipoIgG
Inmunógeno E. coli - derived recombinant Human NOTCH2NLA (Met1-Asn236).
Objetivo Notch homolog 2 N-terminal-like protein A, NOTCH2NL, Notch homolog 2 N-terminal-like protein, N2N, NOTCH2NLA
Purificación Purified by antigen affinity column.
Número de acceso Q7Z3S9
Forma Liquid
Buffer de almacenamiento 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.
Información de uso del producto
Aplicación Dilución
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Estabilidad y almacenamiento Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Fondo

Notch homolog 2 N-terminal-like protein A (NOTCH2NLA) is a ~25 kDa protein. Human-specific protein that promotes neural progenitor proliferation and evolutionary expansion of the brain neocortex by regulating the Notch signaling pathway. Able to promote neural progenitor self-renewal, possibly by down-regulating neuronal differentiation genes, thereby delaying the differentiation of neuronal progenitors and leading to an overall final increase in neuronal production. Acts by enhancing the Notch signaling pathway via two different mechanisms that probably work in parallel to reach the same effect. Enhances Notch signaling pathway in a non-cell-autonomous manner via direct interaction with NOTCH2. Also promotes Notch signaling pathway in a cell-autonomous manner through inhibition of cis DLL1-NOTCH2 interactions, which promotes neuronal differentiation.

1. Florio, M. et al. (2018) eLife 7. PMID: 29561261
2. Fiddes, IT. et al. (2018) Cell 173, 1356-1369.e22. PMID: 29856954
3. Suzuki, IK. et al. (2018) Cell 173, 1370-1384.e16. PMID: 29856955
Nota For research use only.
Imágenes
Referencias
Datasheet
Download SDS PDF
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
Recomendación

Contáctenos para cotizaciones personalizadas, solicitudes en masa y cualquier otro problema.

Correo: [email protected]

Lista de distribuidores

Obtener una cotización gratuita
Anti-NOTCH2NLA Polyclonal Antibody

Acceso rápido

Contáctenos

  • +86-027-65523339

  • [email protected]

  • Edificio C, No. 666, Calle Shendunsi, Wuhan, 430206, China

  • linkedin
  • Ins
  • youtube
  • youtube
Derechos de autor © 2026 abinScience. Todos los derechos reservados. Todos los productos son solo para uso de investigación