

| Numéro de catalogue | HV159014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Description |
Anti-NOTCH4 Polyclonal Antibody (HV159014) is a rabbit polyclonal antibody detecting NOTCH4 in ELISA, IHC, WB. Suitable for Human.
Highlights
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| Reactivité des espèces | Human | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Espèce hôte | Rabbit | ||||||||
| Clonalité | Polyclonal | ||||||||
| Isotype | IgG | ||||||||
| Immunogène | E. coli - derived recombinant Human NOTCH4 (Asp1715-Lys2002). | ||||||||
| Cible | NOTCH4, INT3, hNotch4, Neurogenic locus notch homolog protein 4, Notch 4 | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Numéro d'accès | Q99466 | ||||||||
| Forme | Liquid | ||||||||
| Tampon de stockage | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot. |
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| Informations d'utilisation du produit |
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| Stabilité et stockage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Contexte | Neurogenic locus notch homolog protein 4 (NOTCH4) is a ~209 kDa protein. Functions as a receptor for membrane-bound ligands Jagged1, Jagged2 and Delta1 to regulate cell-fate determination. Upon ligand activation through the released notch intracellular domain (NICD) it forms a transcriptional activator complex with RBPJ/RBPSUH and activates genes of the enhancer of split locus. Affects the implementation of differentiation, proliferation and apoptotic programs. May regulate branching morphogenesis in the developing vascular system. | ||||||||
| Note | For research use only. |



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